2W49

ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE

Summary for 2W49

• Entry DOI: 10.2210/pdb2w49/pdb
• Related: 1ALM 1ATN 1AVS 1BLQ 1EQY 1ESV 1EW7 1H1V 1IJJ 1J6Z 1JC2 1KXP 1LCU 1LOT 1M8Q 1MA9 1MVW 1NCX 1NCY 1NCZ 1NPQ 1NWK 1O18 1O19 1O1A 1O1B 1O1C 1O1D 1O1E 1O1F 1O1G 1P8Z 1PON 1QZ5 1QZ6 1RDW 1RFQ 1RGI 1S22 1SKT 1SMG 1SQK 1T44 1TNP 1TNQ 1TNW 1TNX 1TOP 1UY5 1VDI 1VDJ 1WUA 1Y64 1YTZ 1YV0 1ZAC 2A3Z 2A40 2A41 2A42 2A5X 2ASM 2ASO 2ASP 2D1K 2D3E 2FF3 2FF6 2FXU 2TMA 2V51 2V52 2VCP 2VYP 2W4U 4TNC
• EMDB information: 1561
• Descriptor: TROPONIN C, SKELETAL MUSCLE, TROPONIN T, FAST SKELETAL MUSCLE ISOFORMS, TROPONIN I, FAST SKELETAL MUSCLE, ... (6 entities in total)
• Functional Keywords: contractile protein, isometric contraction
• Biological source: GALLUS GALLUS (CHICKEN); More
• Total number of polymer chains: 36
• Total formula weight: 1100725.09

Authors

Wu, S.,Liu, J.,Reedy, M.C.,Tregear, R.T.,Winkler, H.,Franzini-Armstrong, C.,Sasaki, H.,Lucaveche, C.,Goldman, Y.E.,Reedy, M.K.,Taylor, K.A. (deposition date: 2008-11-24, release date: 2010-05-05, Last modification date: 2024-05-08)

Primary citation

Wu, S.,Liu, J.,Reedy, M.C.,Tregear, R.T.,Winkler, H.,Franzini-Armstrong, C.,Sasaki, H.,Lucaveche, C.,Goldman, Y.E.,Reedy, M.K.,Taylor, K.A.
Electron Tomography of Cryofixed, Isometrically Contracting Insect Flight Muscle Reveals Novel Actin-Myosin Interactions
Plos One, 5:12643-, 2010

PubMed Abstract: Isometric muscle contraction, where force is generated without muscle shortening, is a molecular traffic jam in which the number of actin-attached motors is maximized and all states of motor action are trapped with consequently high heterogeneity. This heterogeneity is a major limitation to deciphering myosin conformational changes in situ.

PubMed: 20844746
DOI: 10.1371/JOURNAL.PONE.0012643

Experimental method

ELECTRON MICROSCOPY (35 Å)