2W49

ISOMETRICALLY CONTRACTING INSECT ASYNCHRONOUS FLIGHT MUSCLE

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0003009	biological_process	skeletal muscle contraction
0	0005509	molecular_function	calcium ion binding
0	0005861	cellular_component	troponin complex
0	0046872	molecular_function	metal ion binding
1	0005861	cellular_component	troponin complex
1	0006937	biological_process	regulation of muscle contraction
2	0005861	cellular_component	troponin complex
3	0003009	biological_process	skeletal muscle contraction
3	0005509	molecular_function	calcium ion binding
3	0005861	cellular_component	troponin complex
3	0046872	molecular_function	metal ion binding
4	0005861	cellular_component	troponin complex
4	0006937	biological_process	regulation of muscle contraction
5	0005861	cellular_component	troponin complex
6	0003009	biological_process	skeletal muscle contraction
6	0005509	molecular_function	calcium ion binding
6	0005861	cellular_component	troponin complex
6	0046872	molecular_function	metal ion binding
7	0005861	cellular_component	troponin complex
7	0006937	biological_process	regulation of muscle contraction
8	0005861	cellular_component	troponin complex
9	0003009	biological_process	skeletal muscle contraction
9	0005509	molecular_function	calcium ion binding
9	0005861	cellular_component	troponin complex
9	0046872	molecular_function	metal ion binding
A	0003779	molecular_function	actin binding
A	0005856	cellular_component	cytoskeleton
A	0005884	cellular_component	actin filament
A	0015629	cellular_component	actin cytoskeleton
A	0031013	molecular_function	troponin I binding
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046982	molecular_function	protein heterodimerization activity
A	0051015	molecular_function	actin filament binding
B	0003779	molecular_function	actin binding
B	0005856	cellular_component	cytoskeleton
B	0005884	cellular_component	actin filament
B	0015629	cellular_component	actin cytoskeleton
B	0031013	molecular_function	troponin I binding
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0046982	molecular_function	protein heterodimerization activity
B	0051015	molecular_function	actin filament binding
C	0003779	molecular_function	actin binding
C	0005856	cellular_component	cytoskeleton
C	0005884	cellular_component	actin filament
C	0015629	cellular_component	actin cytoskeleton
C	0031013	molecular_function	troponin I binding
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0046982	molecular_function	protein heterodimerization activity
C	0051015	molecular_function	actin filament binding
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0001725	cellular_component	stress fiber
D	0003785	molecular_function	actin monomer binding
D	0005509	molecular_function	calcium ion binding
D	0005515	molecular_function	protein binding
D	0005523	molecular_function	tropomyosin binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005856	cellular_component	cytoskeleton
D	0005865	cellular_component	striated muscle thin filament
D	0005884	cellular_component	actin filament
D	0010628	biological_process	positive regulation of gene expression
D	0016787	molecular_function	hydrolase activity
D	0019904	molecular_function	protein domain specific binding
D	0030027	cellular_component	lamellipodium
D	0030041	biological_process	actin filament polymerization
D	0030175	cellular_component	filopodium
D	0030240	biological_process	skeletal muscle thin filament assembly
D	0031013	molecular_function	troponin I binding
D	0031432	molecular_function	titin binding
D	0031941	cellular_component	filamentous actin
D	0032036	molecular_function	myosin heavy chain binding
D	0032432	cellular_component	actin filament bundle
D	0042802	molecular_function	identical protein binding
D	0044297	cellular_component	cell body
D	0048306	molecular_function	calcium-dependent protein binding
D	0048741	biological_process	skeletal muscle fiber development
D	0051017	biological_process	actin filament bundle assembly
D	0090131	biological_process	mesenchyme migration
D	0098723	cellular_component	skeletal muscle myofibril
D	0140660	molecular_function	cytoskeletal motor activator activity
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0001725	cellular_component	stress fiber
E	0003785	molecular_function	actin monomer binding
E	0005509	molecular_function	calcium ion binding
E	0005515	molecular_function	protein binding
E	0005523	molecular_function	tropomyosin binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005856	cellular_component	cytoskeleton
E	0005865	cellular_component	striated muscle thin filament
E	0005884	cellular_component	actin filament
E	0010628	biological_process	positive regulation of gene expression
E	0016787	molecular_function	hydrolase activity
E	0019904	molecular_function	protein domain specific binding
E	0030027	cellular_component	lamellipodium
E	0030041	biological_process	actin filament polymerization
E	0030175	cellular_component	filopodium
E	0030240	biological_process	skeletal muscle thin filament assembly
E	0031013	molecular_function	troponin I binding
E	0031432	molecular_function	titin binding
E	0031941	cellular_component	filamentous actin
E	0032036	molecular_function	myosin heavy chain binding
E	0032432	cellular_component	actin filament bundle
E	0042802	molecular_function	identical protein binding
E	0044297	cellular_component	cell body
E	0048306	molecular_function	calcium-dependent protein binding
E	0048741	biological_process	skeletal muscle fiber development
E	0051017	biological_process	actin filament bundle assembly
E	0090131	biological_process	mesenchyme migration
E	0098723	cellular_component	skeletal muscle myofibril
E	0140660	molecular_function	cytoskeletal motor activator activity
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0001725	cellular_component	stress fiber
F	0003785	molecular_function	actin monomer binding
F	0005509	molecular_function	calcium ion binding
F	0005515	molecular_function	protein binding
F	0005523	molecular_function	tropomyosin binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005856	cellular_component	cytoskeleton
F	0005865	cellular_component	striated muscle thin filament
F	0005884	cellular_component	actin filament
F	0010628	biological_process	positive regulation of gene expression
F	0016787	molecular_function	hydrolase activity
F	0019904	molecular_function	protein domain specific binding
F	0030027	cellular_component	lamellipodium
F	0030041	biological_process	actin filament polymerization
F	0030175	cellular_component	filopodium
F	0030240	biological_process	skeletal muscle thin filament assembly
F	0031013	molecular_function	troponin I binding
F	0031432	molecular_function	titin binding
F	0031941	cellular_component	filamentous actin
F	0032036	molecular_function	myosin heavy chain binding
F	0032432	cellular_component	actin filament bundle
F	0042802	molecular_function	identical protein binding
F	0044297	cellular_component	cell body
F	0048306	molecular_function	calcium-dependent protein binding
F	0048741	biological_process	skeletal muscle fiber development
F	0051017	biological_process	actin filament bundle assembly
F	0090131	biological_process	mesenchyme migration
F	0098723	cellular_component	skeletal muscle myofibril
F	0140660	molecular_function	cytoskeletal motor activator activity
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0001725	cellular_component	stress fiber
G	0003785	molecular_function	actin monomer binding
G	0005509	molecular_function	calcium ion binding
G	0005515	molecular_function	protein binding
G	0005523	molecular_function	tropomyosin binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005856	cellular_component	cytoskeleton
G	0005865	cellular_component	striated muscle thin filament
G	0005884	cellular_component	actin filament
G	0010628	biological_process	positive regulation of gene expression
G	0016787	molecular_function	hydrolase activity
G	0019904	molecular_function	protein domain specific binding
G	0030027	cellular_component	lamellipodium
G	0030041	biological_process	actin filament polymerization
G	0030175	cellular_component	filopodium
G	0030240	biological_process	skeletal muscle thin filament assembly
G	0031013	molecular_function	troponin I binding
G	0031432	molecular_function	titin binding
G	0031941	cellular_component	filamentous actin
G	0032036	molecular_function	myosin heavy chain binding
G	0032432	cellular_component	actin filament bundle
G	0042802	molecular_function	identical protein binding
G	0044297	cellular_component	cell body
G	0048306	molecular_function	calcium-dependent protein binding
G	0048741	biological_process	skeletal muscle fiber development
G	0051017	biological_process	actin filament bundle assembly
G	0090131	biological_process	mesenchyme migration
G	0098723	cellular_component	skeletal muscle myofibril
G	0140660	molecular_function	cytoskeletal motor activator activity
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0001725	cellular_component	stress fiber
H	0003785	molecular_function	actin monomer binding
H	0005509	molecular_function	calcium ion binding
H	0005515	molecular_function	protein binding
H	0005523	molecular_function	tropomyosin binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0005856	cellular_component	cytoskeleton
H	0005865	cellular_component	striated muscle thin filament
H	0005884	cellular_component	actin filament
H	0010628	biological_process	positive regulation of gene expression
H	0016787	molecular_function	hydrolase activity
H	0019904	molecular_function	protein domain specific binding
H	0030027	cellular_component	lamellipodium
H	0030041	biological_process	actin filament polymerization
H	0030175	cellular_component	filopodium
H	0030240	biological_process	skeletal muscle thin filament assembly
H	0031013	molecular_function	troponin I binding
H	0031432	molecular_function	titin binding
H	0031941	cellular_component	filamentous actin
H	0032036	molecular_function	myosin heavy chain binding
H	0032432	cellular_component	actin filament bundle
H	0042802	molecular_function	identical protein binding
H	0044297	cellular_component	cell body
H	0048306	molecular_function	calcium-dependent protein binding
H	0048741	biological_process	skeletal muscle fiber development
H	0051017	biological_process	actin filament bundle assembly
H	0090131	biological_process	mesenchyme migration
H	0098723	cellular_component	skeletal muscle myofibril
H	0140660	molecular_function	cytoskeletal motor activator activity
I	0000166	molecular_function	nucleotide binding
I	0000287	molecular_function	magnesium ion binding
I	0001725	cellular_component	stress fiber
I	0003785	molecular_function	actin monomer binding
I	0005509	molecular_function	calcium ion binding
I	0005515	molecular_function	protein binding
I	0005523	molecular_function	tropomyosin binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005856	cellular_component	cytoskeleton
I	0005865	cellular_component	striated muscle thin filament
I	0005884	cellular_component	actin filament
I	0010628	biological_process	positive regulation of gene expression
I	0016787	molecular_function	hydrolase activity
I	0019904	molecular_function	protein domain specific binding
I	0030027	cellular_component	lamellipodium
I	0030041	biological_process	actin filament polymerization
I	0030175	cellular_component	filopodium
I	0030240	biological_process	skeletal muscle thin filament assembly
I	0031013	molecular_function	troponin I binding
I	0031432	molecular_function	titin binding
I	0031941	cellular_component	filamentous actin
I	0032036	molecular_function	myosin heavy chain binding
I	0032432	cellular_component	actin filament bundle
I	0042802	molecular_function	identical protein binding
I	0044297	cellular_component	cell body
I	0048306	molecular_function	calcium-dependent protein binding
I	0048741	biological_process	skeletal muscle fiber development
I	0051017	biological_process	actin filament bundle assembly
I	0090131	biological_process	mesenchyme migration
I	0098723	cellular_component	skeletal muscle myofibril
I	0140660	molecular_function	cytoskeletal motor activator activity
J	0000166	molecular_function	nucleotide binding
J	0000287	molecular_function	magnesium ion binding
J	0001725	cellular_component	stress fiber
J	0003785	molecular_function	actin monomer binding
J	0005509	molecular_function	calcium ion binding
J	0005515	molecular_function	protein binding
J	0005523	molecular_function	tropomyosin binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0005856	cellular_component	cytoskeleton
J	0005865	cellular_component	striated muscle thin filament
J	0005884	cellular_component	actin filament
J	0010628	biological_process	positive regulation of gene expression
J	0016787	molecular_function	hydrolase activity
J	0019904	molecular_function	protein domain specific binding
J	0030027	cellular_component	lamellipodium
J	0030041	biological_process	actin filament polymerization
J	0030175	cellular_component	filopodium
J	0030240	biological_process	skeletal muscle thin filament assembly
J	0031013	molecular_function	troponin I binding
J	0031432	molecular_function	titin binding
J	0031941	cellular_component	filamentous actin
J	0032036	molecular_function	myosin heavy chain binding
J	0032432	cellular_component	actin filament bundle
J	0042802	molecular_function	identical protein binding
J	0044297	cellular_component	cell body
J	0048306	molecular_function	calcium-dependent protein binding
J	0048741	biological_process	skeletal muscle fiber development
J	0051017	biological_process	actin filament bundle assembly
J	0090131	biological_process	mesenchyme migration
J	0098723	cellular_component	skeletal muscle myofibril
J	0140660	molecular_function	cytoskeletal motor activator activity
K	0000166	molecular_function	nucleotide binding
K	0000287	molecular_function	magnesium ion binding
K	0001725	cellular_component	stress fiber
K	0003785	molecular_function	actin monomer binding
K	0005509	molecular_function	calcium ion binding
K	0005515	molecular_function	protein binding
K	0005523	molecular_function	tropomyosin binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005856	cellular_component	cytoskeleton
K	0005865	cellular_component	striated muscle thin filament
K	0005884	cellular_component	actin filament
K	0010628	biological_process	positive regulation of gene expression
K	0016787	molecular_function	hydrolase activity
K	0019904	molecular_function	protein domain specific binding
K	0030027	cellular_component	lamellipodium
K	0030041	biological_process	actin filament polymerization
K	0030175	cellular_component	filopodium
K	0030240	biological_process	skeletal muscle thin filament assembly
K	0031013	molecular_function	troponin I binding
K	0031432	molecular_function	titin binding
K	0031941	cellular_component	filamentous actin
K	0032036	molecular_function	myosin heavy chain binding
K	0032432	cellular_component	actin filament bundle
K	0042802	molecular_function	identical protein binding
K	0044297	cellular_component	cell body
K	0048306	molecular_function	calcium-dependent protein binding
K	0048741	biological_process	skeletal muscle fiber development
K	0051017	biological_process	actin filament bundle assembly
K	0090131	biological_process	mesenchyme migration
K	0098723	cellular_component	skeletal muscle myofibril
K	0140660	molecular_function	cytoskeletal motor activator activity
L	0000166	molecular_function	nucleotide binding
L	0000287	molecular_function	magnesium ion binding
L	0001725	cellular_component	stress fiber
L	0003785	molecular_function	actin monomer binding
L	0005509	molecular_function	calcium ion binding
L	0005515	molecular_function	protein binding
L	0005523	molecular_function	tropomyosin binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0005856	cellular_component	cytoskeleton
L	0005865	cellular_component	striated muscle thin filament
L	0005884	cellular_component	actin filament
L	0010628	biological_process	positive regulation of gene expression
L	0016787	molecular_function	hydrolase activity
L	0019904	molecular_function	protein domain specific binding
L	0030027	cellular_component	lamellipodium
L	0030041	biological_process	actin filament polymerization
L	0030175	cellular_component	filopodium
L	0030240	biological_process	skeletal muscle thin filament assembly
L	0031013	molecular_function	troponin I binding
L	0031432	molecular_function	titin binding
L	0031941	cellular_component	filamentous actin
L	0032036	molecular_function	myosin heavy chain binding
L	0032432	cellular_component	actin filament bundle
L	0042802	molecular_function	identical protein binding
L	0044297	cellular_component	cell body
L	0048306	molecular_function	calcium-dependent protein binding
L	0048741	biological_process	skeletal muscle fiber development
L	0051017	biological_process	actin filament bundle assembly
L	0090131	biological_process	mesenchyme migration
L	0098723	cellular_component	skeletal muscle myofibril
L	0140660	molecular_function	cytoskeletal motor activator activity
M	0000166	molecular_function	nucleotide binding
M	0000287	molecular_function	magnesium ion binding
M	0001725	cellular_component	stress fiber
M	0003785	molecular_function	actin monomer binding
M	0005509	molecular_function	calcium ion binding
M	0005515	molecular_function	protein binding
M	0005523	molecular_function	tropomyosin binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005856	cellular_component	cytoskeleton
M	0005865	cellular_component	striated muscle thin filament
M	0005884	cellular_component	actin filament
M	0010628	biological_process	positive regulation of gene expression
M	0016787	molecular_function	hydrolase activity
M	0019904	molecular_function	protein domain specific binding
M	0030027	cellular_component	lamellipodium
M	0030041	biological_process	actin filament polymerization
M	0030175	cellular_component	filopodium
M	0030240	biological_process	skeletal muscle thin filament assembly
M	0031013	molecular_function	troponin I binding
M	0031432	molecular_function	titin binding
M	0031941	cellular_component	filamentous actin
M	0032036	molecular_function	myosin heavy chain binding
M	0032432	cellular_component	actin filament bundle
M	0042802	molecular_function	identical protein binding
M	0044297	cellular_component	cell body
M	0048306	molecular_function	calcium-dependent protein binding
M	0048741	biological_process	skeletal muscle fiber development
M	0051017	biological_process	actin filament bundle assembly
M	0090131	biological_process	mesenchyme migration
M	0098723	cellular_component	skeletal muscle myofibril
M	0140660	molecular_function	cytoskeletal motor activator activity
N	0000166	molecular_function	nucleotide binding
N	0000287	molecular_function	magnesium ion binding
N	0001725	cellular_component	stress fiber
N	0003785	molecular_function	actin monomer binding
N	0005509	molecular_function	calcium ion binding
N	0005515	molecular_function	protein binding
N	0005523	molecular_function	tropomyosin binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005856	cellular_component	cytoskeleton
N	0005865	cellular_component	striated muscle thin filament
N	0005884	cellular_component	actin filament
N	0010628	biological_process	positive regulation of gene expression
N	0016787	molecular_function	hydrolase activity
N	0019904	molecular_function	protein domain specific binding
N	0030027	cellular_component	lamellipodium
N	0030041	biological_process	actin filament polymerization
N	0030175	cellular_component	filopodium
N	0030240	biological_process	skeletal muscle thin filament assembly
N	0031013	molecular_function	troponin I binding
N	0031432	molecular_function	titin binding
N	0031941	cellular_component	filamentous actin
N	0032036	molecular_function	myosin heavy chain binding
N	0032432	cellular_component	actin filament bundle
N	0042802	molecular_function	identical protein binding
N	0044297	cellular_component	cell body
N	0048306	molecular_function	calcium-dependent protein binding
N	0048741	biological_process	skeletal muscle fiber development
N	0051017	biological_process	actin filament bundle assembly
N	0090131	biological_process	mesenchyme migration
N	0098723	cellular_component	skeletal muscle myofibril
N	0140660	molecular_function	cytoskeletal motor activator activity
O	0000166	molecular_function	nucleotide binding
O	0000287	molecular_function	magnesium ion binding
O	0001725	cellular_component	stress fiber
O	0003785	molecular_function	actin monomer binding
O	0005509	molecular_function	calcium ion binding
O	0005515	molecular_function	protein binding
O	0005523	molecular_function	tropomyosin binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005856	cellular_component	cytoskeleton
O	0005865	cellular_component	striated muscle thin filament
O	0005884	cellular_component	actin filament
O	0010628	biological_process	positive regulation of gene expression
O	0016787	molecular_function	hydrolase activity
O	0019904	molecular_function	protein domain specific binding
O	0030027	cellular_component	lamellipodium
O	0030041	biological_process	actin filament polymerization
O	0030175	cellular_component	filopodium
O	0030240	biological_process	skeletal muscle thin filament assembly
O	0031013	molecular_function	troponin I binding
O	0031432	molecular_function	titin binding
O	0031941	cellular_component	filamentous actin
O	0032036	molecular_function	myosin heavy chain binding
O	0032432	cellular_component	actin filament bundle
O	0042802	molecular_function	identical protein binding
O	0044297	cellular_component	cell body
O	0048306	molecular_function	calcium-dependent protein binding
O	0048741	biological_process	skeletal muscle fiber development
O	0051017	biological_process	actin filament bundle assembly
O	0090131	biological_process	mesenchyme migration
O	0098723	cellular_component	skeletal muscle myofibril
O	0140660	molecular_function	cytoskeletal motor activator activity
P	0000166	molecular_function	nucleotide binding
P	0000287	molecular_function	magnesium ion binding
P	0001725	cellular_component	stress fiber
P	0003785	molecular_function	actin monomer binding
P	0005509	molecular_function	calcium ion binding
P	0005515	molecular_function	protein binding
P	0005523	molecular_function	tropomyosin binding
P	0005524	molecular_function	ATP binding
P	0005737	cellular_component	cytoplasm
P	0005856	cellular_component	cytoskeleton
P	0005865	cellular_component	striated muscle thin filament
P	0005884	cellular_component	actin filament
P	0010628	biological_process	positive regulation of gene expression
P	0016787	molecular_function	hydrolase activity
P	0019904	molecular_function	protein domain specific binding
P	0030027	cellular_component	lamellipodium
P	0030041	biological_process	actin filament polymerization
P	0030175	cellular_component	filopodium
P	0030240	biological_process	skeletal muscle thin filament assembly
P	0031013	molecular_function	troponin I binding
P	0031432	molecular_function	titin binding
P	0031941	cellular_component	filamentous actin
P	0032036	molecular_function	myosin heavy chain binding
P	0032432	cellular_component	actin filament bundle
P	0042802	molecular_function	identical protein binding
P	0044297	cellular_component	cell body
P	0048306	molecular_function	calcium-dependent protein binding
P	0048741	biological_process	skeletal muscle fiber development
P	0051017	biological_process	actin filament bundle assembly
P	0090131	biological_process	mesenchyme migration
P	0098723	cellular_component	skeletal muscle myofibril
P	0140660	molecular_function	cytoskeletal motor activator activity
Q	0000166	molecular_function	nucleotide binding
Q	0000287	molecular_function	magnesium ion binding
Q	0001725	cellular_component	stress fiber
Q	0003785	molecular_function	actin monomer binding
Q	0005509	molecular_function	calcium ion binding
Q	0005515	molecular_function	protein binding
Q	0005523	molecular_function	tropomyosin binding
Q	0005524	molecular_function	ATP binding
Q	0005737	cellular_component	cytoplasm
Q	0005856	cellular_component	cytoskeleton
Q	0005865	cellular_component	striated muscle thin filament
Q	0005884	cellular_component	actin filament
Q	0010628	biological_process	positive regulation of gene expression
Q	0016787	molecular_function	hydrolase activity
Q	0019904	molecular_function	protein domain specific binding
Q	0030027	cellular_component	lamellipodium
Q	0030041	biological_process	actin filament polymerization
Q	0030175	cellular_component	filopodium
Q	0030240	biological_process	skeletal muscle thin filament assembly
Q	0031013	molecular_function	troponin I binding
Q	0031432	molecular_function	titin binding
Q	0031941	cellular_component	filamentous actin
Q	0032036	molecular_function	myosin heavy chain binding
Q	0032432	cellular_component	actin filament bundle
Q	0042802	molecular_function	identical protein binding
Q	0044297	cellular_component	cell body
Q	0048306	molecular_function	calcium-dependent protein binding
Q	0048741	biological_process	skeletal muscle fiber development
Q	0051017	biological_process	actin filament bundle assembly
Q	0090131	biological_process	mesenchyme migration
Q	0098723	cellular_component	skeletal muscle myofibril
Q	0140660	molecular_function	cytoskeletal motor activator activity
R	0000166	molecular_function	nucleotide binding
R	0000287	molecular_function	magnesium ion binding
R	0001725	cellular_component	stress fiber
R	0003785	molecular_function	actin monomer binding
R	0005509	molecular_function	calcium ion binding
R	0005515	molecular_function	protein binding
R	0005523	molecular_function	tropomyosin binding
R	0005524	molecular_function	ATP binding
R	0005737	cellular_component	cytoplasm
R	0005856	cellular_component	cytoskeleton
R	0005865	cellular_component	striated muscle thin filament
R	0005884	cellular_component	actin filament
R	0010628	biological_process	positive regulation of gene expression
R	0016787	molecular_function	hydrolase activity
R	0019904	molecular_function	protein domain specific binding
R	0030027	cellular_component	lamellipodium
R	0030041	biological_process	actin filament polymerization
R	0030175	cellular_component	filopodium
R	0030240	biological_process	skeletal muscle thin filament assembly
R	0031013	molecular_function	troponin I binding
R	0031432	molecular_function	titin binding
R	0031941	cellular_component	filamentous actin
R	0032036	molecular_function	myosin heavy chain binding
R	0032432	cellular_component	actin filament bundle
R	0042802	molecular_function	identical protein binding
R	0044297	cellular_component	cell body
R	0048306	molecular_function	calcium-dependent protein binding
R	0048741	biological_process	skeletal muscle fiber development
R	0051017	biological_process	actin filament bundle assembly
R	0090131	biological_process	mesenchyme migration
R	0098723	cellular_component	skeletal muscle myofibril
R	0140660	molecular_function	cytoskeletal motor activator activity
S	0000166	molecular_function	nucleotide binding
S	0000287	molecular_function	magnesium ion binding
S	0001725	cellular_component	stress fiber
S	0003785	molecular_function	actin monomer binding
S	0005509	molecular_function	calcium ion binding
S	0005515	molecular_function	protein binding
S	0005523	molecular_function	tropomyosin binding
S	0005524	molecular_function	ATP binding
S	0005737	cellular_component	cytoplasm
S	0005856	cellular_component	cytoskeleton
S	0005865	cellular_component	striated muscle thin filament
S	0005884	cellular_component	actin filament
S	0010628	biological_process	positive regulation of gene expression
S	0016787	molecular_function	hydrolase activity
S	0019904	molecular_function	protein domain specific binding
S	0030027	cellular_component	lamellipodium
S	0030041	biological_process	actin filament polymerization
S	0030175	cellular_component	filopodium
S	0030240	biological_process	skeletal muscle thin filament assembly
S	0031013	molecular_function	troponin I binding
S	0031432	molecular_function	titin binding
S	0031941	cellular_component	filamentous actin
S	0032036	molecular_function	myosin heavy chain binding
S	0032432	cellular_component	actin filament bundle
S	0042802	molecular_function	identical protein binding
S	0044297	cellular_component	cell body
S	0048306	molecular_function	calcium-dependent protein binding
S	0048741	biological_process	skeletal muscle fiber development
S	0051017	biological_process	actin filament bundle assembly
S	0090131	biological_process	mesenchyme migration
S	0098723	cellular_component	skeletal muscle myofibril
S	0140660	molecular_function	cytoskeletal motor activator activity
T	0003779	molecular_function	actin binding
T	0005856	cellular_component	cytoskeleton
T	0005884	cellular_component	actin filament
T	0015629	cellular_component	actin cytoskeleton
T	0031013	molecular_function	troponin I binding
T	0042802	molecular_function	identical protein binding
T	0042803	molecular_function	protein homodimerization activity
T	0046982	molecular_function	protein heterodimerization activity
T	0051015	molecular_function	actin filament binding
U	0003779	molecular_function	actin binding
U	0005856	cellular_component	cytoskeleton
U	0005884	cellular_component	actin filament
U	0015629	cellular_component	actin cytoskeleton
U	0031013	molecular_function	troponin I binding
U	0042802	molecular_function	identical protein binding
U	0042803	molecular_function	protein homodimerization activity
U	0046982	molecular_function	protein heterodimerization activity
U	0051015	molecular_function	actin filament binding
V	0003779	molecular_function	actin binding
V	0005856	cellular_component	cytoskeleton
V	0005884	cellular_component	actin filament
V	0015629	cellular_component	actin cytoskeleton
V	0031013	molecular_function	troponin I binding
V	0042802	molecular_function	identical protein binding
V	0042803	molecular_function	protein homodimerization activity
V	0046982	molecular_function	protein heterodimerization activity
V	0051015	molecular_function	actin filament binding
W	0003779	molecular_function	actin binding
W	0005856	cellular_component	cytoskeleton
W	0005884	cellular_component	actin filament
W	0015629	cellular_component	actin cytoskeleton
W	0031013	molecular_function	troponin I binding
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0046982	molecular_function	protein heterodimerization activity
W	0051015	molecular_function	actin filament binding
X	0003779	molecular_function	actin binding
X	0005856	cellular_component	cytoskeleton
X	0005884	cellular_component	actin filament
X	0015629	cellular_component	actin cytoskeleton
X	0031013	molecular_function	troponin I binding
X	0042802	molecular_function	identical protein binding
X	0042803	molecular_function	protein homodimerization activity
X	0046982	molecular_function	protein heterodimerization activity
X	0051015	molecular_function	actin filament binding
Y	0005861	cellular_component	troponin complex
Y	0006937	biological_process	regulation of muscle contraction
Z	0005861	cellular_component	troponin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 0 1001

Chain	Residue
0	ASP105
0	ASN107
0	ASP109
0	PHE111
0	GLU116

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 0 1002

Chain	Residue
0	GLU152
0	ASP141
0	ASN143
0	ASP145
0	ARG147

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA 0 1003

Chain	Residue
0	ASP29
0	ASP31
0	ASP35
0	GLU40

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 0 1004

Chain	Residue
0	ASP65
0	ASP67
0	SER69
0	THR71
0	ASP73
0	GLU76

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 3 1001

Chain	Residue
3	ASP105
3	ASN107
3	ASP109
3	PHE111
3	GLU116

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 3 1002

Chain	Residue
3	ASP141
3	ASN143
3	ASP145
3	ARG147
3	GLU152

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA 3 1003

Chain	Residue
3	ASP29
3	ASP31
3	ASP35
3	GLU40

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 3 1004

Chain	Residue
3	ASP65
3	ASP67
3	SER69
3	THR71
3	ASP73
3	GLU76

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 6 1001

Chain	Residue
6	ASP105
6	ASN107
6	ASP109
6	PHE111
6	GLU116

---

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 6 1002

Chain	Residue
6	ASP141
6	ASN143
6	ASP145
6	ARG147
6	GLU152

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA 6 1003

Chain	Residue
6	ASP29
6	ASP31
6	ASP35
6	GLU40

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 6 1004

Chain	Residue
6	ASP65
6	ASP67
6	SER69
6	THR71
6	ASP73
6	GLU76

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 9 1001

Chain	Residue
9	ASP105
9	ASN107
9	ASP109
9	PHE111
9	GLU116

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA 9 1002

Chain	Residue
9	ASP141
9	ASN143
9	ASP145
9	ARG147
9	GLU152

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA 9 1003

Chain	Residue
9	ASP29
9	ASP31
9	ASP35
9	GLU40

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA 9 1004

Chain	Residue
9	ASP65
9	ASP67
9	SER69
9	THR71
9	ASP73
9	GLU76

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADGGGDIStkEL

Chain	Residue	Details
0	ASP29-LEU41
0	ASP65-PHE77
0	ASP105-LEU117
0	ASP141-PHE153

---

site_id	PS00326
Number of Residues	9
Details	TROPOMYOSIN Tropomyosins signature. LKEAEtRAE

Chain	Residue	Details
T	LEU225-GLU233

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
Q	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WITKqEYDE

Chain	Residue	Details
Q	TRP356-GLU364

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
Q	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	140
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	140
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	140
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	132
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	148
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	80
Details	Region: {"description":"Involved in binding TNC and actin"}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P58771","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	8
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P04692","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	8
Details	Modified residue: {"description":"Phosphoserine; by DAPK1","evidences":[{"source":"PubMed","id":"278975","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	80
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P04692","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P09493","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	400
Details	Region: {"description":"Interaction with alpha-actinin","evidences":[{"source":"PubMed","id":"8449927","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	16
Details	Modified residue: {"description":"N-acetylaspartate; in Actin, alpha skeletal muscle","evidences":[{"source":"PubMed","id":"1150665","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	32
Details	Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"UniProtKB","id":"P68134","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	16
Details	Modified residue: {"description":"N6-malonyllysine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	16
Details	Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"1150665","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16905096","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"213279","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2395459","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"499690","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1ATN","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NWK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	16
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P68133","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	16
Details	Modified residue: {"description":"ADP-ribosylarginine; by SpvB","evidences":[{"source":"PubMed","id":"16905096","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---