1S22

Absolute Stereochemistry of Ulapualide A

Summary for 1S22

Entry DOI	10.2210/pdb1s22/pdb
Related	1QZ5 1QZ6
Descriptor	Actin, CALCIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	actin; trisoxazole; macrolide; toxin; ulapualide; stereochemistry, structural protein
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Cytoplasm, cytoskeleton: P68135
Total number of polymer chains	1
Total formula weight	43430.06
Authors	Allingham, J.S.,Tanaka, J.,Marriott, G.,Rayment, I. (deposition date: 2004-01-07, release date: 2004-02-17, Last modification date: 2023-08-23)
Primary citation	Allingham, J.S.,Tanaka, J.,Marriott, G.,Rayment, I. Absolute stereochemistry of ulapualide A Org.Lett., 6:597-599, 2004 Cited by PubMed Abstract: [structure: see text] The structure of ulapualide A (1) has been solved by X-ray crystallography in a complex with G-actin. The stereochemical configuration was assigned as 3S,9S,22S,23R,24S,26S,27S,31R,32R,33R. PubMed: 14961632 DOI: 10.1021/ol036458y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation