2FF6

Crystal structure of Gelsolin domain 1:ciboulot domain 2 hybrid in complex with actin

Summary for 2FF6

Entry DOI	10.2210/pdb2ff6/pdb
Descriptor	Gelsolin, CG4944-PC, isoform C, Actin, alpha skeletal muscle, ... (6 entities in total)
Functional Keywords	protein-protein complex, structural protein-contractile protein complex, structural protein/contractile protein
Biological source	Homo sapiens (human) More
Cellular location	Isoform 2: Cytoplasm, cytoskeleton. Isoform 1: Secreted: P06396 Cytoplasm, cytoskeleton: P68135
Total number of polymer chains	3
Total formula weight	62451.33
Authors	Aguda, A.H.,Xue, B.,Robinson, R.C. (deposition date: 2005-12-19, release date: 2006-03-21, Last modification date: 2018-05-23)
Primary citation	Aguda, A.H.,Xue, B.,Irobi, E.,Preat, T.,Robinson, R.C. The Structural Basis of Actin Interaction with Multiple WH2/beta-Thymosin Motif-Containing Proteins Structure, 14:469-476, 2006 Cited by PubMed: 16531231 DOI: 10.1016/j.str.2005.12.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation