2W0Z

Grb2 SH3C (3)

Summary for 2W0Z

Related2H46 1QG1 1CJ1 1BM2 1GFD 1FYR 1BMB 1JYU 1JYQ 1GFC 1X0N 2AOB 1TZE 1AZE 1GRI 2VVK 1IO6 1FHS 1ZFP 2VWF 1GCQ 1GHU 2AOA 1JYR
DescriptorGROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, GRB2-ASSOCIATED-BINDING PROTEIN 2 (3 entities in total)
Functional Keywordssignaling protein, polymorphism, phosphoprotein, golgi apparatus, alternative splicing, host-virus interaction, sh3c, grb2, signaling, sh2 domain, sh3 domain
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationGolgi apparatus (By similarity) P62993
Cytoplasm Q9UQC2
Total number of polymer chains2
Total molecular weight7570.39
Authors
Harkiolaki, M.,Tsirka, T.,Feller, S.M. (deposition date: 2008-10-13, release date: 2009-05-26, Last modification date: 2011-07-13)
Primary citation
Harkiolaki, M.,Tsirka, T.,Lewitzky, M.,Simister, P.C.,Joshi, D.,Bird, L.E.,Jones, E.Y.,O'Reilly, N.,Feller, S.M.
Distinct Binding Modes of Two Epitopes in Gab2 that Interact with the Sh3C Domain of Grb2.
Structure, 17:809-, 2009
PubMed: 19523899 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2009.03.017
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.7 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.210103.6%3.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution