Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2VEN

Structure-based enzyme engineering efforts with an inactive monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties

Summary for 2VEN
Entry DOI10.2210/pdb2ven/pdb
Related1AG1 1DKW 1IIG 1IIH 1KV5 1ML1 1MSS 1MTM 1TPD 1TPE 1TPF 1TRD 1TRI 1TSI 1TTI 1TTJ 2J24 2J27 2V0T 2V2C 2V2D 2V2H 2V5L 2VEI 2VEK 2VEL 2VEM 3TIM 4TIM 5TIM 6TIM
DescriptorGLYCOSOMAL TRIOSEPHOSPHATE ISOMERASE, CITRIC ACID (3 entities in total)
Functional Keywordsisomerase, tim barrel, glycolysis, pentose shunt, gluconeogenesis, lipid synthesis, fatty acid biosynthesis, glycosome
Biological sourceTRYPANOSOMA BRUCEI BRUCEI
Total number of polymer chains2
Total formula weight51510.70
Authors
Alahuhta, M.,Salin, M.,Casteleijn, M.G.,Kemmer, C.,El-Sayed, I.,Augustyns, K.,Neubauer, P.,Wierenga, R.K. (deposition date: 2007-10-25, release date: 2008-02-19, Last modification date: 2023-12-13)
Primary citationAlahuhta, M.,Salin, M.,Casteleijn, M.G.,Kemmer, C.,El-Sayed, I.,Augustyns, K.,Neubauer, P.,Wierenga, R.K.
Structure-Based Protein Engineering Efforts with a Monomeric Tim Variant: The Importance of a Single Point Mutation for Generating an Active Site with Suitable Binding Properties.
Protein Eng.Des.Sel., 21:257-, 2008
Cited by
PubMed: 18239072
DOI: 10.1093/PROTEIN/GZN002
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon