1KV5

Structure of Trypanosoma brucei brucei TIM with the salt-bridge-forming residue Arg191 mutated to Ser

Summary for 1KV5

Descriptortriosephosphate isomerase, glycosomal, 2-PHOSPHOGLYCOLIC ACID, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ... (6 entities in total)
Functional Keywordstim barrel, mutant, salt bridge, isomerase
Biological sourceTrypanosoma brucei brucei
Cellular locationGlycosome P04789
Total number of polymer chains2
Total molecular weight54522.19
Authors
Kursula, I.,Partanen, S.,Lambeir, A.-M.,Wierenga, R.K. (deposition date: 2002-01-25, release date: 2002-03-29, Last modification date: 2011-07-13)
Primary citation
Kursula, I.,Partanen, S.,Lambeir, A.-M.,Wierenga, R.K.
The importance of the conserved Arg191-Asp227 salt bridge of triosephosphate isomerase for folding, stability, and catalysis
FEBS Lett., 518:39-42, 2002
PubMed: 11997014 (PDB entries with the same primary citation)
DOI: 10.1016/S0014-5793(02)02639-X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.65 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.19170 1.3% 1.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25