Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019563 | biological_process | glycerol catabolic process |
| A | 0020015 | cellular_component | glycosome |
| A | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019563 | biological_process | glycerol catabolic process |
| B | 0020015 | cellular_component | glycosome |
| B | 0046166 | biological_process | glyceraldehyde-3-phosphate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PGA A 1350 |
| Chain | Residue |
| A | ASN11 |
| A | LEU232 |
| A | GLY234 |
| A | GLY235 |
| A | HOH4533 |
| A | HOH4548 |
| A | HOH4549 |
| A | HOH4703 |
| A | LYS13 |
| A | HIS95 |
| A | GLU167 |
| A | ALA171 |
| A | ILE172 |
| A | GLY173 |
| A | GLY212 |
| A | SER213 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PGA B 2350 |
| Chain | Residue |
| B | ASN11 |
| B | LYS13 |
| B | HIS95 |
| B | GLU167 |
| B | ALA171 |
| B | ILE172 |
| B | GLY173 |
| B | GLY212 |
| B | SER213 |
| B | LEU232 |
| B | GLY234 |
| B | GLY235 |
| B | HOH5617 |
| B | HOH5620 |
| B | HOH5631 |
| B | HOH5757 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 5600 |
| Chain | Residue |
| B | SER32 |
| B | ILE33 |
| B | ASN34 |
| B | HIS35 |
| B | LYS247 |
| B | GLN250 |
| B | HOH5964 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DTT A 3450 |
| Chain | Residue |
| A | LEU144 |
| A | TRP193 |
| A | HOH4616 |
| B | ALA148 |
| B | TRP193 |
| B | LYS197 |
| B | HOH5683 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 4500 |
| Chain | Residue |
| A | LYS155 |
| A | LYS156 |
| A | HOH4573 |
| A | HOH4659 |
| A | HOH4861 |
| B | HOH5935 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 4501 |
| Chain | Residue |
| A | HOH4800 |
| B | LYS176 |
| B | GLN182 |
| B | HOH5825 |
| B | HOH5887 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 4502 |
| Chain | Residue |
| B | GLN38 |
| B | ASN89 |
| B | TRP90 |
| B | HOH5880 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 4503 |
| Chain | Residue |
| A | GLN181 |
| A | GLU185 |
| A | HOH4588 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA165-GLY175 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Electrophile"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| A | LYS13 | |
| A | HIS95 | |
| A | ASN11 | |
| A | GLU167 | |
| A | GLY173 | |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1hti |
| Chain | Residue | Details |
| B | LYS13 | |
| B | HIS95 | |
| B | ASN11 | |
| B | GLU167 | |
| B | GLY173 | |
