1DKW

CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE

Summary for 1DKW

Related1ML1 1MSS 5TIM
DescriptorTRIOSEPHOSPHATE ISOMERASE, TERTIARY-BUTYL ALCOHOL (3 entities in total)
Functional Keywordstim barrel, modified loop-8, isomerase
Biological sourceTrypanosoma brucei brucei
Cellular locationGlycosome P04789
Total number of polymer chains2
Total molecular weight51723.07
Authors
Norledge, B.V.,Lambeir, A.M.,Abagyan, R.A.,Rottman, A.,Fernandez, A.M.,Filimonov, V.V.,Peter, M.G.,Wierenga, R.K. (deposition date: 1999-12-08, release date: 2000-11-03, Last modification date: 2011-07-13)
Primary citation
Norledge, B.V.,Lambeir, A.M.,Abagyan, R.A.,Rottmann, A.,Fernandez, A.M.,Filimonov, V.V.,Peter, M.G.,Wierenga, R.K.
Modeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (loop 8) of triosephosphate isomerase: toward a new substrate specificity.
Proteins, 42:383-389, 2001
PubMed: 11151009 (PDB entries with the same primary citation)
DOI: 10.1002/1097-0134(20010215)42:3<383::AID-PROT80>3.0.CO;2-G
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.65 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers130 10.5% 0.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
170172
PDB entries from 2020-10-21