1DKW

CRYSTAL STRUCTURE OF TRIOSE-PHOSPHATE ISOMERASE WITH MODIFIED SUBSTRATE BINDING SITE

Summary for 1DKW

• Entry DOI: 10.2210/pdb1dkw/pdb
• Related: 1ML1 1MSS 5TIM
• Descriptor: TRIOSEPHOSPHATE ISOMERASE, TERTIARY-BUTYL ALCOHOL (3 entities in total)
• Functional Keywords: tim barrel, modified loop-8, isomerase
• Biological source: Trypanosoma brucei brucei
• Cellular location: Glycosome: P04789
• Total number of polymer chains: 2
• Total formula weight: 51723.07

Authors

Norledge, B.V.,Lambeir, A.M.,Abagyan, R.A.,Rottman, A.,Fernandez, A.M.,Filimonov, V.V.,Peter, M.G.,Wierenga, R.K. (deposition date: 1999-12-08, release date: 2000-11-03, Last modification date: 2024-02-07)

• Primary citation: Norledge, B.V.,Lambeir, A.M.,Abagyan, R.A.,Rottmann, A.,Fernandez, A.M.,Filimonov, V.V.,Peter, M.G.,Wierenga, R.K.; Modeling, mutagenesis, and structural studies on the fully conserved phosphate-binding loop (loop 8) of triosephosphate isomerase: toward a new substrate specificity.; Proteins, 42:383-389, 2001; PubMed: 11151009; DOI: 10.1002/1097-0134(20010215)42:3<383::AID-PROT80>3.0.CO;2-G

Experimental method

X-RAY DIFFRACTION (2.65 Å)