2V9Y

Human aminoimidazole ribonucleotide synthetase

Summary for 2V9Y

• Entry DOI: 10.2210/pdb2v9y/pdb
• Related: 1MEJ 1MEN 1MEO 1NJS 1ZLX 1ZLY
• Descriptor: PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE, SULFATE ION (3 entities in total)
• Functional Keywords: multifunctional enzyme, structural genomics consortium, nucleotide-binding, purine biosynthesis, sgc, airs, gart, ligase, transferase, atp-binding, aminoimidazole ribonucleotide synthetase, phosphorylation, purine metabolism, structural genomics
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 71948.22

Authors

Welin, M.,Lehtio, L.,Arrowsmith, C.H.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Herman, M.D.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Moche, M.,Nyman, T.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,Tresaugues, L.,van den Berg, S.,Weigelt, J.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2007-08-28, release date: 2007-09-11, Last modification date: 2023-12-13)

• Primary citation: Welin, M.,Grossmann, J.G.,Flodin, S.,Nyman, T.,Stenmark, P.,Tresaugues, L.,Kotenyova, T.,Johansson, I.,Nordlund, P.,Lehtio, L.; Structural Studies of Tri-Functional Human Gart.; Nucleic Acids Res., 38:7308-, 2010; PubMed: 20631005; DOI: 10.1093/NAR/GKQ595

Experimental method

X-RAY DIFFRACTION (2.1 Å)