2V9Y

Human aminoimidazole ribonucleotide synthetase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE	polymer	334	35830.0	2	UniProt (P22102) Pfam (PF00586) Pfam (PF02769) In PDB	HOMO SAPIENS (HUMAN)	AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE, AIRS, PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE, AIR SYNTHASE
2	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
3		water	water		18.0	170	Chemie (HOH)

Sequence modifications

A, B: 461 - 466 (PDB: 2V9Y)
A, B: 467 - 794 (UniProt: P22102)

PDB	External Database	Details
Gly 752	Asp 752	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71660.0
Non-Polymers*	Number of molecules	3
	Total formula weight	288.2
All*	Total formula weight	71948.2

*Water molecules are not included.