2B1G
Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
Summary for 2B1G
Entry DOI | 10.2210/pdb2b1g/pdb |
Related | 1G8M 1M9N 1OZ0 1PKX 1PL0 1THZ 2b0w 2b1i |
Descriptor | Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, POTASSIUM ION, ... (5 entities in total) |
Functional Keywords | atic, impch, structure-base, transition state analogue, inhibitor, transferase, hydrolase |
Biological source | Gallus gallus (chicken) |
Total number of polymer chains | 4 |
Total formula weight | 258977.70 |
Authors | Xu, L.,Chong, Y.,Hwang, I.,D'Onofrio, A.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A. (deposition date: 2005-09-15, release date: 2006-11-21, Last modification date: 2023-08-23) |
Primary citation | Xu, L.,Chong, Y.,Hwang, I.,D'Onofrio, A.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A. Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase. J.Biol.Chem., 282:13033-13046, 2007 Cited by PubMed: 17324932DOI: 10.1074/jbc.M607293200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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