1M9N

CRYSTAL STRUCTURE OF THE HOMODIMERIC BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME AVIAN ATIC IN COMPLEX WITH AICAR AND XMP AT 1.93 ANGSTROMS.

Summary for 1M9N

Related1G8M
DescriptorAICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, POTASSIUM ION, AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, ... (5 entities in total)
Functional Keywordshomodimer, 2 functional domains; impch domain = alpha/beta/alpha; aicar tfase = 2 alpha/beta/alpha domains, 1 alpha + beta domain, transferase, hydrolase
Biological sourceGallus gallus (chicken)
Total number of polymer chains2
Total molecular weight134823.22
Authors
Wolan, D.W.,Greasly, S.E.,Beardsley, G.P.,Wilson, I.A. (deposition date: 2002-07-29, release date: 2003-01-07, Last modification date: 2011-07-13)
Primary citation
Wolan, D.W.,Greasly, S.E.,Beardsley, G.P.,Wilson, I.A.
Structural Insights into the Avian AICAR Transformylase Mechanism.
Biochemistry, 41:15505-15513, 2002
PubMed: 12501179 (PDB entries with the same primary citation)
DOI: 10.1021/bi020505x
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.93 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers90.3%3.4%7.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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