1M9N
CRYSTAL STRUCTURE OF THE HOMODIMERIC BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME AVIAN ATIC IN COMPLEX WITH AICAR AND XMP AT 1.93 ANGSTROMS.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE | polymer | 613 | 66669.1 | 2 | UniProt (P31335) Pfam (PF02142) Pfam (PF01808) | Gallus gallus (chicken) | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH [INCLUDES PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE (AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE (INOSINICASE, IMP SYNTHETASE, ATIC)] |
| 2 | C, F (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) PubChem (813) | |||
| 3 | D, G (A, B) | AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE | non-polymer | 338.2 | 2 | Chemie (AMZ) PubChem (16760280) PubChem (25322835) PubChem (29971658) PubChem (29971663) PubChem (46874858) PubChem (46936194) PubChem (69015652) PubChem (200) PubChem (65110) PubChem (90004537) PubChem (92209412) PubChem (92209413) PubChem (92209414) PubChem (92209415) PubChem (159841653) PubChem (162938701) PubChem (163812830) PubChem (171699377) PubChem (173757272) | |||
| 4 | E, H (A, B) | XANTHOSINE-5'-MONOPHOSPHATE | non-polymer | 365.2 | 2 | Chemie (XMP) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 511 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 593 (UniProt: P31335)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | expression tag |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | insertion |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 133338.2 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1485.0 | |
| All* | Total formula weight | 134823.2 |
