1G8M
CRYSTAL STRUCTURE OF AVIAN ATIC, A BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME IN PURINE BIOSYNTHESIS AT 1.75 ANG. RESOLUTION
Summary for 1G8M
| Entry DOI | 10.2210/pdb1g8m/pdb |
| Descriptor | AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE, POTASSIUM ION, GUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | homodimer, 2 functional domains; impch domain = alpha/beta/alpha; aicar tfase = 2 alpha/beta/alpha domains, 1 alpha + beta domain, transferase, hydrolase |
| Biological source | Gallus gallus (chicken) |
| Total number of polymer chains | 2 |
| Total formula weight | 130374.73 |
| Authors | Greasley, S.E.,Horton, P.,Beardsley, G.P.,Benkovic, S.J.,Wilson, I.A. (deposition date: 2000-11-17, release date: 2001-04-27, Last modification date: 2017-10-04) |
| Primary citation | Greasley, S.E.,Horton, P.,Ramcharan, J.,Beardsley, G.P.,Benkovic, S.J.,Wilson, I.A. Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Nat.Struct.Biol., 8:402-406, 2001 Cited by PubMed: 11323713DOI: 10.1038/87555 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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