1G8M
CRYSTAL STRUCTURE OF AVIAN ATIC, A BIFUNCTIONAL TRANSFORMYLASE AND CYCLOHYDROLASE ENZYME IN PURINE BIOSYNTHESIS AT 1.75 ANG. RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AICAR TRANSFORMYLASE-IMP CYCLOHYDROLASE | polymer | 593 | 64966.7 | 2 | UniProt (P31335) Pfam (PF02142) Pfam (PF01808) | Gallus gallus (chicken) | BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH [INCLUDES PHOSPHORIBOSYLAMINOIMIDAZOLECARBOXAMIDE FORMYLTRANSFERASE (AICAR TRANSFORMYLASE) AND IMP CYCLOHYDROLASE (INOSINICASE, IMP SYNTHETASE, ATIC)] |
| 2 | C, E (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D (A) | GUANOSINE-5'-MONOPHOSPHATE | non-polymer | 363.2 | 1 | Chemie (5GP) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 744 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 593 (UniProt: P31335)
| PDB | External Database | Details |
|---|---|---|
| Mse 61 | Met 61 | cloning artifact |
| Mse 89 | Met 89 | cloning artifact |
| Mse 159 | Met 159 | cloning artifact |
| Mse 211 | Met 211 | cloning artifact |
| Mse 289 | Met 289 | cloning artifact |
| Mse 313 | Met 313 | cloning artifact |
| Mse 368 | Met 368 | cloning artifact |
| Mse 388 | Met 388 | cloning artifact |
| Mse 477 | Met 477 | cloning artifact |
| Mse 512 | Met 512 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 129933.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 441.4 | |
| All* | Total formula weight | 130374.7 |
