1PKX
Crystal Structure of human ATIC in complex with XMP
Summary for 1PKX
| Entry DOI | 10.2210/pdb1pkx/pdb |
| Related | 1P4R 1PL0 |
| Descriptor | Bifunctional purine biosynthesis protein PURH, POTASSIUM ION, XANTHOSINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | atic, aicar transformylase, imp cyclohydrolase, xanthosine monophosphate, purine biosynthesis, transferase, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 4 |
| Total formula weight | 259661.69 |
| Authors | Wolan, D.W.,Cheong, C.G.,Greasley, S.E.,Wilson, I.A. (deposition date: 2003-06-06, release date: 2004-02-17, Last modification date: 2023-08-16) |
| Primary citation | Wolan, D.W.,Cheong, C.G.,Greasley, S.E.,Wilson, I.A. Structural Insights into the Human and Avian IMP Cyclohydrolase Mechanism via Crystal Structures with the Bound XMP Inhibitor. Biochemistry, 43:1171-1183, 2004 Cited by PubMed: 14756553DOI: 10.1021/bi030162i PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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