2B1G
Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Bifunctional purine biosynthesis protein PURH | polymer | 593 | 64497.7 | 4 | UniProt (P31335) Pfam (PF02142) Pfam (PF01808) | Gallus gallus (chicken) | |
| 2 | E, I (A, C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 3 | F, H, J, K (A, B, C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 4 | G, L (A, D) | 7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE | non-polymer | 320.3 | 2 | Chemie (13A) | |||
| 5 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 426 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 257990.8 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 986.9 | |
| All* | Total formula weight | 258977.7 |
