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2B1G

Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase

Summary for 2B1G
Entry DOI10.2210/pdb2b1g/pdb
Related1G8M 1M9N 1OZ0 1PKX 1PL0 1THZ 2b0w 2b1i
DescriptorBifunctional purine biosynthesis protein PURH, PHOSPHATE ION, POTASSIUM ION, ... (5 entities in total)
Functional Keywordsatic, impch, structure-base, transition state analogue, inhibitor, transferase, hydrolase
Biological sourceGallus gallus (chicken)
Total number of polymer chains4
Total formula weight258977.70
Authors
Xu, L.,Chong, Y.,Hwang, I.,D'Onofrio, A.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A. (deposition date: 2005-09-15, release date: 2006-11-21, Last modification date: 2023-08-23)
Primary citationXu, L.,Chong, Y.,Hwang, I.,D'Onofrio, A.,Amore, K.,Beardsley, G.P.,Li, C.,Olson, A.J.,Boger, D.L.,Wilson, I.A.
Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase.
J.Biol.Chem., 282:13033-13046, 2007
Cited by
PubMed: 17324932
DOI: 10.1074/jbc.M607293200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.1 Å)
Structure validation

217705

数据于2024-03-27公开中

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