1VSO
Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex With the Antagonist (S)-ATPO at 1.85 A resolution
Summary for 1VSO
Entry DOI | 10.2210/pdb1vso/pdb |
Related | 1N0T 1YCJ 2F34 2F35 2PBW |
Descriptor | Glutamate receptor, ionotropic kainate 1, (S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACID, GLYCEROL, ... (4 entities in total) |
Functional Keywords | antagonist complex, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P22756 |
Total number of polymer chains | 1 |
Total formula weight | 29522.80 |
Authors | Hald, H.,Naur, P.,Gajhede, M.,Kastrup, J.S. (deposition date: 2007-03-29, release date: 2007-07-03, Last modification date: 2023-08-23) |
Primary citation | Hald, H.,Naur, P.,Pickering, D.S.,Sprogoe, D.,Madsen, U.,Timmermann, D.B.,Ahring, P.K.,Liljefors, T.,Schousboe, A.,Egebjerg, J.,Gajhede, M.,Kastrup, J.S. Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid. J.Biol.Chem., 282:25726-25736, 2007 Cited by PubMed: 17581823DOI: 10.1074/jbc.M700137200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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