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1VSO

Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex With the Antagonist (S)-ATPO at 1.85 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutamate receptor, ionotropic kainate 1polymer25729108.51UniProt (P22756)
Pfam (PF10613)
Pfam (PF00060)
Rattus norvegicus (Norway rat)Glutamate receptor 5, GluR-5, GluR5
2B
(A)
(S)-2-AMINO-3-(5-TERT-BUTYL-3-(PHOSPHONOMETHOXY)-4-ISOXAZOLYL)PROPIONIC ACIDnon-polymer322.31Chemie (AT1)
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
waterwater18.0204Chemie (HOH)
Sequence modifications
A: 2 - 116 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 1-expression tag
Gly 34Ala 477SEE REMARK 999
A: 119 - 257 (UniProt: P22756)
PDBExternal DatabaseDetails
Gly 117-linker
Thr 118-linker
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29108.5
Non-Polymers*Number of molecules2
Total formula weight414.3
All*Total formula weight29522.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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