1VSO

Crystal Structure of the Ligand-Binding Core of iGluR5 in Complex With the Antagonist (S)-ATPO at 1.85 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE AT1 A 258

Chain	Residue
A	GLU13
A	THR192
A	SER193
A	TYR216
A	GOL400
A	HOH416
A	HOH446
A	HOH537
A	HOH544
A	HOH583
A	TYR61
A	PRO88
A	LEU89
A	THR90
A	ARG95
A	GLY140
A	SER141
A	GLU190

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 400

Chain	Residue
A	TYR61
A	AT1258
A	HOH451
A	HOH471
A	HOH537
A	HOH542

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0007744|PDB:1YCJ

Chain	Residue	Details
A	PRO88
A	THR90
A	SER141
A	THR142

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:15710405, ECO:0000269|PubMed:15721240, ECO:0007744|PDB:1YCJ

Chain	Residue	Details
A	ARG95
A	GLU190

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC => ECO:0000255

Chain	Residue	Details
A	SER162

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PKC => ECO:0000255

Chain	Residue	Details
A	THR198

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site_id	SWS_FT_FI5
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN3
A	ASN203

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