1UZU

Glycogen Phosphorylase b in complex with indirubin-5'-sulphonate

1UZU の概要

• エントリーDOI: 10.2210/pdb1uzu/pdb
• 関連するPDBエントリー: 1A8I 1ABB 1AXR 1B4D 1BX3 1C50 1C8K 1C8L 1E1Y 1FS4 1FTQ 1FTW 1FTY 1FU4 1FU7 1FU8 1GFZ 1GG8 1GGN 1GPA 1GPB 1GPY 1H5U 1HLF 1K06 1K08 1KTI 1LWN 1LWO 1NOI 1NOJ 1NOK 1P29 1P2B 1P2D 1P2G 1PYG 2AMV 2GPA 2GPB 2GPN 2PRI 2PRJ 2SKC 2SKD 2SKE 3AMV 3GPB 4GPB 5GPB 6GPB 7GPB 8GPB 9GPB
• 分子名称: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, PYRIDOXAL-5'-PHOSPHATE, 2',3-DIOXO-1,1',2',3-TETRAHYDRO-2,3'-BIINDOLE-5'-SULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: transferase, glycosyltransferase, glycogen metabolism, carbohydrate metabolism, pyridoxal phosphate
• 由来する生物種: ORYCTOLAGUS CUNICULUS (RABBIT)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 97880.67

構造登録者

Kosmopoulou, M.N.,Leonidas, D.D.,Chrysina, E.D.,Bischler, N.,Eisenbrand, G.,Sakarellos, C.E.,Pauptit, R.,Oikonomakos, N.G. (登録日: 2004-03-16, 公開日: 2004-05-27, 最終更新日: 2023-12-13)

• 主引用文献: Kosmopoulou, M.N.,Leonidas, D.D.,Chrysina, E.D.,Bischler, N.,Eisenbrand, G.,Sakarellos, C.E.,Pauptit, R.,Oikonomakos, N.G.; Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex.; Eur. J. Biochem., 271:2280-2290, 2004; PubMed: 15153119; DOI: 10.1111/j.1432-1033.2004.04173.x

実験手法

X-RAY DIFFRACTION (2.3 Å)