1GFZ
FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE
Summary for 1GFZ
Entry DOI | 10.2210/pdb1gfz/pdb |
Descriptor | GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, INOSINIC ACID, ... (5 entities in total) |
Functional Keywords | glycogen phosphorylase, glycogen metabolism, diabetes, flavopiridol, inhibitor site, transferase |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 98080.74 |
Authors | Oikonomakos, N.G.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. (deposition date: 2000-06-29, release date: 2000-07-26, Last modification date: 2023-12-27) |
Primary citation | Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site. J.Biol.Chem., 275:34566-34573, 2000 Cited by PubMed: 10924512DOI: 10.1074/jbc.M004485200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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