1GFZ

FLAVOPIRIDOL INHIBITS GLYCOGEN PHOSPHORYLASE BY BINDING AT THE INHIBITOR SITE

Summary for 1GFZ

Entry DOI	10.2210/pdb1gfz/pdb
Descriptor	GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE, INOSINIC ACID, ... (5 entities in total)
Functional Keywords	glycogen phosphorylase, glycogen metabolism, diabetes, flavopiridol, inhibitor site, transferase
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	1
Total formula weight	98080.74
Authors	Oikonomakos, N.G.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. (deposition date: 2000-06-29, release date: 2000-07-26, Last modification date: 2023-12-27)
Primary citation	Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site. J.Biol.Chem., 275:34566-34573, 2000 Cited by PubMed: 10924512 DOI: 10.1074/jbc.M004485200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation