1LWN

Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution

Summary for 1LWN

Related1H5U 1LWO
Descriptorglycogen phosphorylase, ALPHA-D-GLUCOSE, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywordstype 2 diabetes, glycogen phosphorylase, inhibitor, new allosteric site, transferase
Biological sourceOryctolagus cuniculus (rabbit)
Total number of polymer chains1
Total molecular weight97798.48
Authors
Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.,Leonidas, D.D. (deposition date: 2002-06-01, release date: 2002-06-19, Last modification date: 2011-07-13)
Primary citation
Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.N.,Leonidas, D.D.
Crystal structure of rabbit muscle glycogen phosphorylase a in complex with a potential hypoglycaemic drug at 2.0 A resolution
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647:325-332, 2003
PubMed: 12686153 (PDB entries with the same primary citation)
DOI: 10.1016/S1570-9639(03)00085-2
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers60.2%7.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution