1PW2
APO STRUCTURE OF HUMAN CYCLIN-DEPENDENT KINASE 2
Summary for 1PW2
Entry DOI | 10.2210/pdb1pw2/pdb |
Related | 1AQ1 1B39 1CKP 1DI8 1DM2 1E1V 1E1X 1E9H 1FIN 1FVT 1FVV 1G5S 1GIH 1GZ8 1HCK 1HCL 1JSV 1JVP 1KE5 1KE6 1KE7 1KE8 1KE9 |
Descriptor | Cell division protein kinase 2 (2 entities in total) |
Functional Keywords | protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition, transferase, serine/threonine-protein kinase, atp-binding, 3d-structure. |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 33976.49 |
Authors | Wu, S.Y.,McNae, I.,Kontopidis, G.,McClue, S.J.,McInnes, C.,Stewart, K.J.,Wang, S.,Zheleva, D.I.,Marriage, H.,Lane, D.P.,Taylor, P.,Fischer, P.M.,Walkinshaw, M.D. (deposition date: 2003-06-30, release date: 2003-12-09, Last modification date: 2023-08-16) |
Primary citation | Wu, S.Y.,McNae, I.,Kontopidis, G.,McClue, S.J.,McInnes, C.,Stewart, K.J.,Wang, S.,Zheleva, D.I.,Marriage, H.,Lane, D.P.,Taylor, P.,Fischer, P.M.,Walkinshaw, M.D. Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop. Structure, 11:399-410, 2003 Cited by PubMed: 12679018DOI: 10.1016/S0969-2126(03)00060-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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