1DGK

MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE

Summary for 1DGK

Related1CZA 1HKB 1HKC
DescriptorHEXOKINASE TYPE I, ALPHA-D-GLUCOSE, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordsbrain hexokinase, mammalian hexokinase 1, sugar kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion outer membrane P19367
Total number of polymer chains1
Total molecular weight103866.67
Authors
Aleshin, A.E.,Liu, X.,Kirby, C.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1999-11-24, release date: 2000-03-08, Last modification date: 2018-01-31)
Primary citation
Aleshin, A.E.,Kirby, C.,Liu, X.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B.
Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296:1001-1015, 2000
PubMed: 10686099 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1999.3494
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers90.2%3.5%2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1dgk
no rotation
Molmil generated image of 1dgk
rotated about x axis by 90°
Molmil generated image of 1dgk
rotated about y axis by 90°