1CZA

MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE, GLUCOSE-6-PHOSPHATE, AND ADP

Summary for 1CZA

Related1HKB 1HKC
DescriptorHEXOKINASE TYPE I, ALPHA-D-GLUCOSE, ALPHA-D-GLUCOSE-6-PHOSPHATE, ... (5 entities in total)
Functional Keywordsstructurally homologous domains, transferase
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion outer membrane P19367
Total number of polymer chains1
Total molecular weight103894.79
Authors
Aleshin, A.E.,Liu, X.,Kirby, C.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1999-09-01, release date: 2000-03-06, Last modification date: 2011-07-13)
Primary citation
Aleshin, A.E.,Kirby, C.,Liu, X.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B.
Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation.
J.Mol.Biol., 296:1001-1015, 2000
PubMed: 10686099 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1999.3494
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers60.2%2.5%6.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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