1HKB

CRYSTAL STRUCTURE OF RECOMBINANT HUMAN BRAIN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE

Summary for 1HKB

Entry DOI	10.2210/pdb1hkb/pdb
Descriptor	D-GLUCOSE 6-PHOSPHOTRANSFERASE, beta-D-glucopyranose, 6-O-phosphono-alpha-D-glucopyranose, ... (5 entities in total)
Functional Keywords	phosphotransferase, glycolysis, allosteric enzyme, glucose, glucose-6-phosphate
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	207171.56
Authors	Aleshin, A.E.,Zeng, C.,Burenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. (deposition date: 1997-12-01, release date: 1998-06-03, Last modification date: 2024-04-03)
Primary citation	Aleshin, A.E.,Zeng, C.,Bourenkov, G.P.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B. The mechanism of regulation of hexokinase: new insights from the crystal structure of recombinant human brain hexokinase complexed with glucose and glucose-6-phosphate. Structure, 6:39-50, 1998 Cited by PubMed: 9493266 DOI: 10.1016/S0969-2126(98)00006-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation