1HKC

RECOMBINANT HUMAN HEXOKINASE TYPE I COMPLEXED WITH GLUCOSE AND PHOSPHATE

Summary for 1HKC

DescriptorD-GLUCOSE 6-PHOSPHOTRANSFERASE, BETA-D-GLUCOSE, PHOSPHATE ION, ... (5 entities in total)
Functional Keywordsphosphotransferase, glycolysis, allosteric enzyme, glucose, phosphate
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion outer membrane P19367
Total number of polymer chains1
Total molecular weight103072.35
Authors
Aleshin, A.E.,Honzatko, R.B. (deposition date: 1998-07-01, release date: 1998-11-11, Last modification date: 2011-07-13)
Primary citation
Aleshin, A.E.,Zeng, C.,Bartunik, H.D.,Fromm, H.J.,Honzatko, R.B.
Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphate.
J.Mol.Biol., 282:345-357, 1998
PubMed: 9735292 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1998.2017
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers151.0%9.9%0.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution