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1DGK

MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1NHEXOKINASE TYPE Ipolymer917102557.01UniProt (P19367)
Pfam (PF00349)
Pfam (PF03727)
In PDB
Homo sapiens (human)HK I, BRAIN FORM HEXOKINASE
2Nalpha-D-glucopyranosenon-polymer180.22Chemie (GLC)
3NPHOSPHATE IONnon-polymer95.01Chemie (PO4)
4NADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
5waterwater18.094Chemie (HOH)
Sequence modifications
N: 1 - 917 (UniProt: P19367)
PDBExternal DatabaseDetails
Glu 240Ala 280engineered mutation
Arg 243Ala 283engineered mutation
Tyr 284Gly 284engineered mutation
Ala 536Thr 536engineered mutation
Asp 730Asn 730conflict
Leu 776Met 776conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight102557.0
Non-Polymers*Number of molecules5
Total formula weight1309.7
All*Total formula weight103866.7
*Water molecules are not included.

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PDB entries from 2024-03-27

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