1DGK
MUTANT MONOMER OF RECOMBINANT HUMAN HEXOKINASE TYPE I WITH GLUCOSE AND ADP IN THE ACTIVE SITE
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | N | HEXOKINASE TYPE I | polymer | 917 | 102557.0 | 1 | UniProt (P19367) Pfam (PF00349) Pfam (PF03727) In PDB | Homo sapiens (human) | HK I, BRAIN FORM HEXOKINASE |
2 | N | alpha-D-glucopyranose | non-polymer | 180.2 | 2 | Chemie (GLC) | |||
3 | N | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
4 | N | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
5 | water | water | 18.0 | 94 | Chemie (HOH) |
Sequence modifications
N: 1 - 917 (UniProt: P19367)
PDB | External Database | Details |
---|---|---|
Glu 240 | Ala 280 | engineered mutation |
Arg 243 | Ala 283 | engineered mutation |
Tyr 284 | Gly 284 | engineered mutation |
Ala 536 | Thr 536 | engineered mutation |
Asp 730 | Asn 730 | conflict |
Leu 776 | Met 776 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 102557.0 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1309.7 | |
All* | Total formula weight | 103866.7 |