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4UNT
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BU of 4unt by Molmil
Induced monomer of the Mcg variable domain
Descriptor: IG LAMBDA CHAIN V-II REGION MGC, SULFATE ION
Authors:Brumshtein, B, Esswein, S.R, Landau, M, Ryan, C.M, Whitelegge, J.P, Phillips, M.L, Cascio, D, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2014-05-30
Release date:2014-08-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Formation of Amyloid Fibers by Monomeric Light-Chain Variable Domains.
J.Biol.Chem., 289, 2014
2X44
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BU of 2x44 by Molmil
Structure of a strand-swapped dimeric form of CTLA-4
Descriptor: CYTOTOXIC T-LYMPHOCYTE PROTEIN 4
Authors:Sonnen, A.F.-P, Yu, C, Evans, E.J, Stuart, D.I, Davis, S.J, Gilbert, R.J.C.
Deposit date:2010-01-28
Release date:2010-04-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Domain Metastability: A Molecular Basis for Immunoglobulin Deposition?
J.Mol.Biol., 399, 2010
7OUN
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BU of 7oun by Molmil
Structure of human PD-L1 in complex with macrocyclic inhibitor
Descriptor: Programmed cell death 1 ligand 1, macrocyclic peptide
Authors:Zyla, E, Dubin, G.
Deposit date:2021-06-12
Release date:2021-09-15
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Characterization of a Macrocyclic Peptide Modulator of the PD-1/PD-L1 Immune Checkpoint Axis.
Molecules, 26, 2021
7AH1
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BU of 7ah1 by Molmil
L19 diabody fragment from immunocytokine L19-IL2
Descriptor: Anti-(ED-B) scFV
Authors:Ongaro, T, Guarino, S.R, Scietti, L, Palamini, M, Wulhfard, S, Villa, A, Neri, D, Forneris, F.
Deposit date:2020-09-23
Release date:2021-02-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inference of molecular structure for characterization and improvement of clinical grade immunocytokines.
J.Struct.Biol., 213, 2021
3KHQ
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BU of 3khq by Molmil
Crystal structure of murine Ig-beta (CD79b) in the monomeric form
Descriptor: B-cell antigen receptor complex-associated protein beta chain, CITRATE ANION, GLUTATHIONE, ...
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-30
Release date:2010-08-25
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
3KG5
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BU of 3kg5 by Molmil
Crystal structure of human Ig-beta homodimer
Descriptor: B-cell antigen receptor complex-associated protein beta chain
Authors:Radaev, S, Sun, P.D.
Deposit date:2009-10-28
Release date:2010-08-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural and Functional Studies of Igalphabeta and Its Assembly with the B Cell Antigen Receptor.
Structure, 18, 2010
4Y88
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BU of 4y88 by Molmil
Crystal structure of the N-terminal domain of CEACAM8
Descriptor: 1,3-PROPANDIOL, CHLORIDE ION, Carcinoembryonic antigen-related cell adhesion molecule 8, ...
Authors:Bonsor, D.A, Sundberg, E.J.
Deposit date:2015-02-16
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Diverse oligomeric states of CEACAM IgV domains.
Proc.Natl.Acad.Sci.USA, 112, 2015
6IGO
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BU of 6igo by Molmil
Crystal structure of myelin protein zero-like protein 1 (MPZL1)
Descriptor: Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-25
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.746 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
5MJ0
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BU of 5mj0 by Molmil
Extracellular domain of human CD83 - cubic crystal form
Descriptor: CD83 antigen
Authors:Klingl, S, Egerer-Sieber, C, Schmid, B, Muller, Y.A.
Deposit date:2016-11-29
Release date:2017-03-29
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.
J. Mol. Biol., 429, 2017
6PLL
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BU of 6pll by Molmil
Crystal structure of the ZIG-8 IG1 homodimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Zwei Ig domain protein zig-8
Authors:Cheng, S, Ozkan, E.
Deposit date:2019-07-01
Release date:2020-07-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.693 Å)
Cite:Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6IGT
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BU of 6igt by Molmil
MPZL1 mutant - V145G, Q146K, P147T and G148S
Descriptor: Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-26
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
6IGW
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BU of 6igw by Molmil
MPZL1 mutant - S86G, V145G, Q146K,P147T,G148S
Descriptor: Myelin protein zero-like protein 1
Authors:Yu, T.
Deposit date:2018-09-26
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.979 Å)
Cite:Structural and biochemical studies of the extracellular domain of Myelin protein zero-like protein 1
Biochem. Biophys. Res. Commun., 506, 2018
5MJ1
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BU of 5mj1 by Molmil
Extracellular domain of human CD83 - rhombohedral crystal form
Descriptor: CD83 antigen, DI(HYDROXYETHYL)ETHER
Authors:Klingl, S, Egerer-Sieber, C, Schmid, B, Weiler, S, Muller, Y.A.
Deposit date:2016-11-29
Release date:2017-03-29
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Extracellular Domain of the Human Dendritic Cell Surface Marker CD83.
J. Mol. Biol., 429, 2017
6ISC
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BU of 6isc by Molmil
complex structure of mCD226-ecto and hCD155-D1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD226 antigen, Poliovirus receptor
Authors:Wang, H, Qi, J, Zhang, S, Li, Y, Tan, S, Gao, G.F.
Deposit date:2018-11-16
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5FEB
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BU of 5feb by Molmil
Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain
Descriptor: GLYCEROL, Sodium channel subunit beta-2
Authors:Das, S, Van Petegem, F.
Deposit date:2015-12-16
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Binary architecture of the Nav1.2-beta 2 signaling complex.
Elife, 5, 2016
5F7H
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BU of 5f7h by Molmil
Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine
Descriptor: CALCIUM ION, PHOSPHOSERINE, T-cell immunoglobulin and mucin domain-containing protein 4
Authors:Gao, G.F, Lu, G, Wang, H, Qi, J.
Deposit date:2015-12-08
Release date:2016-02-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Chin.Sci.Bull., 60, 2015
5FFL
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BU of 5ffl by Molmil
Crystal structure of mouse CD300lf at 1.6 Angstroms resolution.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CD300 antigen-like family member F, ...
Authors:Nelson, C.A, Fremont, D.H.
Deposit date:2015-12-18
Release date:2016-08-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Discovery of a proteinaceous cellular receptor for a norovirus.
Science, 353, 2016
5FDY
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BU of 5fdy by Molmil
Crystal structure of the Voltage-gated Sodium Channel Beta 2 subunit extracellular domain, C72A/C75A mutant
Descriptor: GLYCEROL, Sodium channel subunit beta-2
Authors:Das, S, Van Petegem, F.
Deposit date:2015-12-16
Release date:2016-03-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Binary architecture of the Nav1.2-beta 2 signaling complex.
Elife, 5, 2016
7SJQ
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BU of 7sjq by Molmil
Ex silico engineering of cystine-dense peptides yielding a potent bispecific T-cell engager
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cystine-dense peptide, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2021-10-18
Release date:2022-06-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
5X8M
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BU of 5x8m by Molmil
PD-L1 in complex with durvalumab
Descriptor: Programmed cell death 1 ligand 1, durvalumab heavy chain, durvalumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (2.661 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5X8L
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BU of 5x8l by Molmil
PD-L1 in complex with atezolizumab
Descriptor: Programmed cell death 1 ligand 1, atezolizumab heavy chain, atezolizumab light chain
Authors:Heo, Y.S, Lee, H.T.
Deposit date:2017-03-03
Release date:2017-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular mechanism of PD-1/PD-L1 blockade via anti-PD-L1 antibodies atezolizumab and durvalumab
Sci Rep, 7, 2017
5XJ3
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BU of 5xj3 by Molmil
Complex structure of ipilimumab-scFv and CTLA-4
Descriptor: Cytotoxic T-lymphocyte protein 4, ipilimumab-VH, ipilimumab-VL
Authors:He, M, Chai, Y, Qi, J, Tong, Z, Tan, S, Gao, G.F.
Deposit date:2017-04-29
Release date:2018-04-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Remarkably similar CTLA-4 binding properties of therapeutic ipilimumab and tremelimumab antibodies
Oncotarget, 8, 2017
5XOF
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BU of 5xof by Molmil
Crystal structure of human paired immunoglobulin-like type 2 receptor alpha with synthesized glycopeptide I
Descriptor: N-acetyl-alpha-neuraminic acid-(2-6)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Paired immunoglobulin-like type 2 receptor alpha, Peptide from Nitric oxide synthase, ...
Authors:Furukawa, A, Kakita, K, Yamada, T, Ishizuka, M, Sakamoto, J, Hatori, N, Maeda, N, Ohsaka, F, Saitoh, T, Nomura, T, Kuroki, K, Nambu, H, Arase, H, Matsunaga, H, Anada, M, Ose, T, Hashimoto, S, Maenaka, K.
Deposit date:2017-05-28
Release date:2017-10-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.963 Å)
Cite:Structural and thermodynamic analyses reveal critical features of glycopeptide recognition by the human PILR alpha immune cell receptor.
J. Biol. Chem., 292, 2017
5XAX
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BU of 5xax by Molmil
Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta4 subunit explain its role in cell-cell adhesion
Descriptor: GLYCEROL, Sodium channel subunit beta-4
Authors:Shimizu, H, Yokoyama, S.
Deposit date:2017-03-15
Release date:2017-07-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Parallel homodimer structures of the extracellular domains of the voltage-gated sodium channel beta 4 subunit explain its role in cell-cell adhesion
J. Biol. Chem., 292, 2017
7QUI
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BU of 7qui by Molmil
Crystal structure of the N-terminal domain of Siglec-8 in complex with sulfonamide sialoside analogue
Descriptor: (2~{S},4~{S},5~{R},6~{R})-5-acetamido-2-[(2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-acetamido-2-(hydroxymethyl)-4,6-bis(oxidanyl)oxan-3-yl]oxy-3,5-bis(oxidanyl)-6-(sulfooxymethyl)oxan-4-yl]oxy-6-[(1~{R},2~{R})-3-(naphthalen-2-ylsulfonylamino)-1,2-bis(oxidanyl)propyl]-4-oxidanyl-oxane-2-carboxylic acid, Sialic acid-binding Ig-like lectin 8
Authors:Lenza, M.P, Oyenarte, I, Atxabal, U, Nycholat, C, Franconetti, A, Quintana, J.I, Delgado, S, Unione, L, Paulson, J, Jimenez-Barbero, J, Ereno-Orbea, J.
Deposit date:2022-01-18
Release date:2023-01-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3.352 Å)
Cite:Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.
Jacs Au, 3, 2023

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