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1D1N
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BU of 1d1n by Molmil
SOLUTION STRUCTURE OF THE FMET-TRNAFMET BINDING DOMAIN OF BECILLUS STEAROTHERMOPHILLUS TRANSLATION INITIATION FACTOR IF2
Descriptor: INITIATION FACTOR 2
Authors:Meunier, S, Spurio, S, Czisch, M, Wechselberger, R, Gueunneugues, M.
Deposit date:1999-09-20
Release date:2000-09-20
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure of the fMet-tRNA(fMet)-binding domain of B. stearothermophilus initiation factor IF2.
EMBO J., 19, 2000
3E1Y
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BU of 3e1y by Molmil
Crystal structure of human eRF1/eRF3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1
Authors:Cheng, Z, Lim, M, Kong, C, Song, H.
Deposit date:2008-08-05
Release date:2009-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural insights into eRF3 and stop codon recognition by eRF1
Genes Dev., 23, 2009
1HA3
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BU of 1ha3 by Molmil
ELONGATION FACTOR TU IN COMPLEX WITH aurodox
Descriptor: BETA-MERCAPTOETHANOL, ELONGATION FACTOR TU, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Vogeley, L, Palm, G.J, Mesters, J.R, Hilgenfeld, R.
Deposit date:2001-03-26
Release date:2001-05-15
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational Change of Elongation Factor TU Induced by Antibiotic Binding: Crystal Structure of the Complex between EF-TU:Gdp and Aurodox
J.Biol.Chem., 276, 2001
5OT7
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BU of 5ot7 by Molmil
Elongation factor G-ribosome complex captures in the absence of inhibitors.
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Mace, K, Giudice, E, Chat, S, Gillet, R.
Deposit date:2017-08-21
Release date:2018-02-14
Last modified:2018-04-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:The structure of an elongation factor G-ribosome complex captured in the absence of inhibitors.
Nucleic Acids Res., 46, 2018
7O9K
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BU of 7o9k by Molmil
Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the MALSU module, GTPBP5 and mtEF-Tu
Descriptor: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ...
Authors:Valentin Gese, G, Hallberg, B.M.
Deposit date:2021-04-16
Release date:2021-06-30
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for late maturation steps of the human mitoribosomal large subunit.
Nat Commun, 12, 2021
6VLZ
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BU of 6vlz by Molmil
Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI)
Descriptor: 12s rRNA, 16s rRNA, 28S ribosomal protein S10, ...
Authors:Sharma, M.R, Koripella, R.K, Agrawal, R.K.
Deposit date:2020-01-27
Release date:2020-08-05
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.97 Å)
Cite:Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Nat Commun, 11, 2020
5FG3
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BU of 5fg3 by Molmil
Crystal structure of GDP-bound aIF5B from Aeropyrum pernix
Descriptor: GUANOSINE-5'-DIPHOSPHATE, Probable translation initiation factor IF-2
Authors:Murakami, R, Miyoshi, T, Uchiumi, T, Ito, K.
Deposit date:2015-12-20
Release date:2016-05-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of translation initiation factor 5B from the crenarchaeon Aeropyrum pernix.
Proteins, 84, 2016
5XJC
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BU of 5xjc by Molmil
Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhang, X, Yan, C, Hang, J, Finci, I.L, Lei, J, Shi, Y.
Deposit date:2017-04-30
Release date:2017-07-05
Last modified:2020-10-14
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:An Atomic Structure of the Human Spliceosome
Cell, 169, 2017
8CH6
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BU of 8ch6 by Molmil
Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex).
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ...
Authors:Cretu, C, Schmitzova, J, Pena, V.
Deposit date:2023-02-07
Release date:2023-05-10
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
1QZD
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BU of 1qzd by Molmil
EF-Tu.kirromycin coordinates fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome
Descriptor: Elongation factor Tu
Authors:Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J.
Deposit date:2003-09-16
Release date:2003-11-04
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (10 Å)
Cite:Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
2RDO
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BU of 2rdo by Molmil
50S subunit with EF-G(GDPNP) and RRF bound
Descriptor: 23S RIBOSOMAL RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ...
Authors:Gao, N, Zavialov, A.V, Ehrenberg, M, Frank, J.
Deposit date:2007-09-24
Release date:2008-03-04
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:Specific interaction between EF-G and RRF and its implication for GTP-dependent ribosome splitting into subunits.
J.Mol.Biol., 374, 2007
3MMP
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BU of 3mmp by Molmil
Structure of the Qb replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins
Descriptor: (2S)-1-[3-{[(2R)-2-hydroxypropyl]oxy}-2,2-bis({[(2R)-2-hydroxypropyl]oxy}methyl)propoxy]propan-2-ol, Elongation factor Tu 2, Elongation factor Ts, ...
Authors:Kidmose, R.T, Vasiliev, N.N, Chetverin, A.B, Knudsen, C.R, Andersen, G.R.
Deposit date:2010-04-20
Release date:2010-06-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Qbeta replicase, an RNA-dependent RNA polymerase consisting of viral and host proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
7UG7
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BU of 7ug7 by Molmil
70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B
Descriptor: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ...
Authors:Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N.
Deposit date:2022-03-24
Release date:2022-05-18
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation.
Proc.Natl.Acad.Sci.USA, 119, 2022
4LBY
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BU of 4lby by Molmil
Identifying ligand binding hot spots in proteins using brominated fragments
Descriptor: AMMONIUM ION, Elongation factor Tu-A, MAGNESIUM ION, ...
Authors:Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P.
Deposit date:2013-06-21
Release date:2013-09-11
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Identifying ligand-binding hot spots in proteins using brominated fragments.
Acta Crystallogr.,Sect.F, 69, 2013
4Q7J
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BU of 4q7j by Molmil
Complex structure of viral RNA polymerase
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu 1, ...
Authors:Takeshita, D.
Deposit date:2014-04-25
Release date:2014-08-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular insights into replication initiation by Q beta replicase using ribosomal protein S1.
Nucleic Acids Res., 42, 2014
6FF7
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BU of 6ff7 by Molmil
human Bact spliceosome core structure
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, BUD13 homolog, ...
Authors:Haselbach, D, Komarov, I, Agafonov, D, Hartmuth, K, Graf, B, Kastner, B, Luehrmann, R, Stark, H.
Deposit date:2018-01-03
Release date:2019-03-13
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and Conformational Dynamics of the Human Spliceosomal BactComplex.
Cell, 172, 2018
4M1K
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BU of 4m1k by Molmil
Crystal structure of elongation factor G (EFG)
Descriptor: Elongation factor G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Liu, G, Dong, J, Gong, W, Qin, Y.
Deposit date:2013-08-02
Release date:2014-08-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.952 Å)
Cite:Crystal structure of elongation factor G (EFG)
To be published
7F67
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BU of 7f67 by Molmil
eIF2B-SFSV NSs-2-eIF2
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
Authors:Kashiwagi, K, Ito, T.
Deposit date:2021-06-24
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.59 Å)
Cite:eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
1AIP
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BU of 1aip by Molmil
EF-TU EF-TS COMPLEX FROM THERMUS THERMOPHILUS
Descriptor: ELONGATION FACTOR TS, ELONGATION FACTOR TU
Authors:Wang, Y, Jiang, Y, Meyering-Voss, M, Sprinzl, M, Sigler, P.B.
Deposit date:1997-04-22
Release date:1997-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the EF-Tu.EF-Ts complex from Thermus thermophilus.
Nat.Struct.Biol., 4, 1997
7F66
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BU of 7f66 by Molmil
eIF2B-SFSV NSs-1-eIF2
Descriptor: Eukaryotic translation initiation factor 2 subunit 1, Eukaryotic translation initiation factor 2 subunit 3, Non-structural protein NS-S, ...
Authors:Kashiwagi, K, Ito, T.
Deposit date:2021-06-24
Release date:2021-12-01
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:eIF2B-capturing viral protein NSs suppresses the integrated stress response.
Nat Commun, 12, 2021
6EZE
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BU of 6eze by Molmil
The open conformation of E.coli Elongation Factor Tu in complex with GDPNP.
Descriptor: DI(HYDROXYETHYL)ETHER, Elongation factor Tu 2, GLYCEROL, ...
Authors:Johansen, J.S, Blaise, M, Thirup, S.S.
Deposit date:2017-11-15
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:E. coli elongation factor Tu bound to a GTP analogue displays an open conformation equivalent to the GDP-bound form.
Nucleic Acids Res., 46, 2018
4R71
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BU of 4r71 by Molmil
Structure of the Qbeta holoenzyme complex in the P1211 crystal form
Descriptor: 30S ribosomal protein S1, Elongation factor Ts, Elongation factor Tu, ...
Authors:Gytz, H, Seweryn, P, Kutlubaeva, Z, Chetverin, A.B, Brodersen, D.E, Knudsen, C.R.
Deposit date:2014-08-26
Release date:2015-09-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Structural basis for RNA-genome recognition during bacteriophage Q beta replication.
Nucleic Acids Res., 43, 2015
1B23
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BU of 1b23 by Molmil
E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex
Descriptor: CYSTEINE, CYSTEINYL TRNA, ELONGATION FACTOR TU, ...
Authors:Nissen, P, Kjeldgaard, M, Thirup, S, Nyborg, J.
Deposit date:1998-12-04
Release date:1998-12-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of Cys-tRNACys-EF-Tu-GDPNP reveals general and specific features in the ternary complex and in tRNA.
Structure Fold.Des., 7, 1999
6BK7
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BU of 6bk7 by Molmil
1.83 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-404) of Elongation Factor G from Enterococcus faecalis
Descriptor: Elongation factor G, SODIUM ION
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Cardona-Correa, A, Grimshaw, S, Kwon, K, Anderson, W.F, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-11-07
Release date:2017-11-22
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:1.83 Angstrom Resolution Crystal Structure of N-terminal Fragment (residues 1-404) of Elongation Factor G from Enterococcus faecalis.
To be Published
6D9J
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BU of 6d9j by Molmil
Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1.
Descriptor: 18S rRNA, 28S rRNA, 5.8S rRNA, ...
Authors:Pisareva, V.P, Pisarev, A.V, Fernandez, I.S.
Deposit date:2018-04-30
Release date:2018-06-06
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES.
Elife, 7, 2018

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