4ENE
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STRUCTURE OF THE N- AND C-TERMINAL TRIMMED CLC-EC1 CL-/H+ ANTIPORTER AND FAB COMPLEX
Descriptor:H(+)/Cl(-) exchange transporter ClcA, heavy chain of Fab fragment, light chain of Fab fragment, ...
Authors:Lim, H.H., Shane, T., Miller, C.
Deposit date:2012-04-13
Release date:2012-12-26
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Intracellular proton access in a cl(-)/h(+) antiporter.
Plos Biol., 10, 2012
1OTS
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL AND FAB COMPLEX
Descriptor:Voltage-gated ClC-type chloride channel eriC, Fab fragment (heavy chain), Fab fragment (light chain), ...
Authors:Dutzler, R., Campbell, E.B., MacKinnon, R.
Deposit date:2003-03-22
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
3DET
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STRUCTURE OF THE E148A, Y445A DOUBLY UNGATED MUTANT OF E.COLI CLC_EC1, CL-/H+ ANTIPORTER
Descriptor:H(+)/Cl(-) exchange transporter clcA, Fab fragment, Heavy chain, ...
Authors:Jayaram, H., Accardi, A., Wu, F., Williams, C., Miller, C.
Deposit date:2008-06-10
Release date:2008-06-17
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger
Proc.Natl.Acad.Sci.USA, 105, 2008
4KKL
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STRUCTURE OF THE E148A MUTANT OF CLC-EC1 DELTA NC CONSTRUCT IN 100MM FLUORIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Stockbridge, R.B., Lim, H.-H., Miller, C.
Deposit date:2013-05-06
Release date:2013-08-21
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KK8
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STRUCTURE OF THE E148Q MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN 100MM FLUORIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KJQ
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STRUCTURE OF THE CLC-EC1 DELTANC CONSTRUCT IN 100MM FLUORIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.875 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
3EJZ
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STRUCTURE OF E203V MUTANT E.COLI CL-/H+ EXCHANGER, CLC-EC1
Descriptor:H(+)/Cl(-) exchange transporter clcA, Fab fragment, Heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2008-09-18
Release date:2009-02-17
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Intracellular proton-transfer mutants in a CLC Cl-/H+ exchanger.
J.Gen.Physiol., 133, 2009
4LOU
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STRUCTURE OF THE E148Q MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN THE ABSENCE OF HALIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab heavy chain, Fab light chain
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-07-13
Release date:2013-08-28
Method:X-RAY DIFFRACTION (2.981 Å)
Cite:A fluoride interloper in a CLC-type Cl /H+ antiporter
Nat.Chem.Biol., 2013
4KK9
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STRUCTURE OF THE E148A MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN 100MM FLUORIDE AND 2MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (2.997 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
1KPL
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CRYSTAL STRUCTURE OF THE CLC CHLORIDE CHANNEL FROM S. TYPHIMURIUM
Descriptor:putative ClC family, chlorine transport protein, CHLORIDE ION, ...
Authors:Dutzler, R., Campbell, E.B., Cadene, M., Chait, B.T., MacKinnon, R.
Deposit date:2001-12-31
Release date:2002-01-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity.
Nature, 415, 2002
1OTT
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STRUCTURE OF THE ESCHERICHIA COLI CLC CHLORIDE CHANNEL E148A MUTANT AND FAB COMPLEX
Descriptor:Voltage-gated ClC-type chloride channel eriC, Fab fragment (Heavy chain), Fab fragment (Light chain), ...
Authors:Dutzler, R., Campbell, E.B., MacKinnon, R.
Deposit date:2003-03-23
Release date:2003-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Gating the Selectivity Filter in ClC Chloride Channels
Science, 300, 2003
4KKA
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STRUCTURE OF THE E148A MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN 100MM FLUORIDE AND 20MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
6D0J
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CRYSTAL STRUCTURE OF A CLC-TYPE FLUORIDE/PROTON ANTIPORTER
Descriptor:CLC-type fluoride/proton antiporter, Monobody, DECYL-BETA-D-MALTOPYRANOSIDE, ...
Authors:Last, N.B., Stockbridge, R.B., Wilson, A.E., Shane, T., Kolmakova-Partensky, L., Koide, A., Koide, S., Miller, C.
Deposit date:2018-04-10
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
4FG6
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STRUCTURE OF ECCLC E148A MUTANT IN GLUTAMATE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab fragment (Heavy chain), Fab fragment (Light chain)
Authors:Feng, L., MacKinnon, R.
Deposit date:2012-06-04
Release date:2012-07-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (3.019 Å)
Cite:Molecular mechanism of proton transport in CLC Cl-/H+ exchange transporters.
Proc.Natl.Acad.Sci.USA, 109, 2012
4KKB
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STRUCTURE OF THE E148A MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN 20MM FLUORIDE AND 20MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.021 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KJW
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STRUCTURE OF THE CLC-EC1 DELTANC CONSTRUCT IN 100MM FLUORIDE AND 20MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.03 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
2EXY
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CRYSTAL STRUCTURE OF THE E148Q MUTANT OF ECCLC, FAB COMPLEXED IN ABSENCE OF BOUND IONS
Descriptor:H(+)/Cl(-) exchange transporter clcA, Fab Fragment (Heavy Chain), Fab Fragment (Light Chain)
Authors:Lobet, S., Dutzler, R.
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ion-binding properties of the ClC chloride selectivity filter.
Embo J., 25, 2006
2H2P
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CRYSTAL STRUCTURE OF CLC-EC1 IN COMPLEX WITH FAB FRAGMENT IN SECN-
Descriptor:CLC Cl transporter, FAB fragment, heavy chain, ...
Authors:Nguitragool, W., Miller, C.
Deposit date:2006-05-19
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006
2H2S
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CRYSTAL STRUCTURE OF E148A MUTANT OF CLC-EC1 IN SECN-
Descriptor:CLC Cl transporter, FAB fragment, heavy chain, ...
Authors:Nguitragool, W., Miller, C.
Deposit date:2006-05-19
Release date:2006-05-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006
2R9H
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CRYSTAL STRUCTURE OF Q207C MUTANT OF CLC-EC1 IN COMPLEX WITH FAB
Descriptor:H(+)/Cl(-) exchange transporter clcA, Fab fragment, CHLORIDE ION
Authors:Nguitragool, W., Miller, C.
Deposit date:2007-09-12
Release date:2007-11-20
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of Q207C Mutant of CLC-ec1 in complex with Fab
To be Published
3NMO
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CRYSTAL STRUCTURE OF AN ENGINEERED MONOMERIC CLC-EC1 CL-/H+ TRANSPORTER
Descriptor:H(+)/Cl(-) exchange transporter clcA, CHLORIDE ION
Authors:Robertson, J.L., Kolmakova-Partensky, L., Miller, C.
Deposit date:2010-06-22
Release date:2010-07-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Design, function and structure of a monomeric ClC transporter.
Nature, 468, 2010
6D0N
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CRYSTAL STRUCTURE OF A CLC-TYPE FLUORIDE/PROTON ANTIPORTER, V319G MUTANT
Descriptor:CLC-type fluoride/proton antiporter, Monobody, DECYL-BETA-D-MALTOPYRANOSIDE, ...
Authors:Last, N.B., Stockbridge, R.B., Wilson, A.E., Shane, T., Kolmakova-Partensky, L., Koide, A., Koide, S., Miller, C.
Deposit date:2018-04-10
Release date:2018-07-04
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:A CLC-type F-/H+antiporter in ion-swapped conformations.
Nat. Struct. Mol. Biol., 25, 2018
5HD8
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CRYSTAL STRUCTURE OF DISULFIDE CROSS-LINKED D417C CLC-EC1
Descriptor:H(+)/Cl(-) exchange transporter ClcA, FAB FRAGMENT (HEAVY CHAIN), FAB FRAGMENT (LIGHT CHAIN), ...
Authors:Mathews, I.I., Khantwal, C.M., Maduke, M.
Deposit date:2016-01-05
Release date:2017-01-18
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Conformational change in CLC transporters: beyond the rotation of Gluex
To be published
4KK5
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STRUCTURE OF THE CLC-EC1 DELTANC CONSTRUCT IN 20MM FLUORIDE AND 20MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-11-13
Method:X-RAY DIFFRACTION (3.171 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
4KKC
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STRUCTURE OF THE E148A MUTANT OF CLC-EC1 DELTANC CONSTRUCT IN 20MM BROMIDE
Descriptor:H(+)/Cl(-) exchange transporter ClcA, Fab, heavy chain, ...
Authors:Lim, H.-H., Miller, C.
Deposit date:2013-05-05
Release date:2013-08-21
Last modified:2013-12-04
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Fluoride-dependent interruption of the transport cycle of a CLC Cl(-)/H(+) antiporter.
Nat.Chem.Biol., 9, 2013
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