6V2J

Crystal structure of ClC-ec1 triple mutant (E113Q, E148Q, E203Q)

Summary for 6V2J

• Entry DOI: 10.2210/pdb6v2j/pdb
• Descriptor: H(+)/Cl(-) exchange transporter ClcA, CHLORIDE ION (3 entities in total)
• Functional Keywords: chloride transporters, clc-ec1, transport protein
• Biological source: Escherichia coli (strain K12)
• Total number of polymer chains: 1
• Total formula weight: 52218.76

Authors

Maduke, M.,Mathews, I.I.,Chavan, T.S. (deposition date: 2019-11-24, release date: 2020-05-20, Last modification date: 2023-10-11)

• Primary citation: Chavan, T.S.,Cheng, R.C.,Jiang, T.,Mathews, I.I.,Stein, R.A.,Koehl, A.,Mchaourab, H.S.,Tajkhorshid, E.,Maduke, M.; A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl - /H + transport cycle.; Elife, 9:-, 2020; PubMed: 32310757; DOI: 10.7554/eLife.53479

Experimental method

X-RAY DIFFRACTION (2.62 Å)