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4U68
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BU of 4u68 by Molmil
Crystal structure of Rhino chromodomain in complex with H3K9me3
Descriptor: H3K9me3, Rhino
Authors:Yu, B.W, Huang, Y.
Deposit date:2014-07-28
Release date:2015-08-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into Rhino-mediated germline piRNA cluster formation
Cell Res., 25, 2015
6MHA
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BU of 6mha by Molmil
dHP1 Chromodomain Y24W variant bound to histone H3 peptide containing trimethyllysine
Descriptor: Heterochromatin protein 1, histone H3 peptide containing trimethyllysine, H3K9me3
Authors:Brustad, E.M, Krone, M.W, Albanese, K.I, Waters, M.L.
Deposit date:2018-09-17
Release date:2019-09-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.497 Å)
Cite:Thermodynamic consequences of Tyr to Trp mutations in the cation-pi-mediated binding of trimethyllysine by the HP1 chromodomain
Chem Sci, 11, 2020
1X3P
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BU of 1x3p by Molmil
3D solution structure of the Chromo-3 domain of cpSRP43
Descriptor: cpSRP43
Authors:Leena, P.S.T, Kumar, T.K.S, Sivaraja, V, Henry, R, Yu, C.
Deposit date:2005-05-10
Release date:2005-09-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:3D Solution Structure of the Chromo-3 domain of cpSRP43
To be Published
5AFW
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BU of 5afw by Molmil
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, ...
Authors:Metzger, E, Willmann, D, McMillan, J, Petroll, K, Metzger, P, Gerhardt, S, vonMaessenhausen, A, Schott, A.K, Espejo, A, Eberlin, A, Wohlwend, D, Schuele, K.M, Schleicher, M, Perner, S, Bedford, M.T, Dengjel, J, Flaig, R, Einsle, O, Schuele, R.
Deposit date:2015-01-26
Release date:2016-01-13
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Nat.Struct.Mol.Biol., 23, 2016
1GUW
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BU of 1guw by Molmil
STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1beta IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES
Descriptor: CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1
Authors:Nielsen, P.R, Nietlispach, D, Mott, H.R, Callaghan, J.M, Bannister, A, Kouzarides, T, Murzin, A.G, Murzina, N.V, Laue, E.D.
Deposit date:2002-02-01
Release date:2002-03-12
Last modified:2025-04-09
Method:SOLUTION NMR
Cite:Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9
Nature, 416, 2002
4HAE
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BU of 4hae by Molmil
Crystal structure of the CDYL2-chromodomain
Descriptor: Chromodomain Y-like protein 2, SULFATE ION, UNKNOWN ATOM OR ION
Authors:Qin, S, Dombrovski, L, Tempel, W, Dong, A, Xu, C, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
Deposit date:2012-09-26
Release date:2012-10-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the CDYL2-chromodomain
To be Published
5JJZ
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BU of 5jjz by Molmil
Chromo domain of human Chromodomain Protein, Y-Like 2
Descriptor: Chromodomain Y-like protein 2, LYS-LYS-LYS-ALA-ARG-MLY-SER-ALA-GLY-ALA-ALA-LYS-TYR
Authors:DONG, A, DOMBROVSKI, L, LOPPNAU, P, TEMPEL, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, MIN, J, WU, H, Structural Genomics Consortium (SGC)
Deposit date:2016-04-25
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of CDYL2 domain of human CDYL2 protein
to be published
1G6Z
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BU of 1g6z by Molmil
SOLUTION STRUCTURE OF THE CLR4 CHROMO DOMAIN
Descriptor: CLR4 PROTEIN
Authors:Horita, D.A, Ivanova, A.V, Altieri, A.S, Klar, A.J, Byrd, R.A.
Deposit date:2000-11-08
Release date:2001-04-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure, domain features, and structural implications of mutants of the chromo domain from the fission yeast histone methyltransferase Clr4.
J.Mol.Biol., 307, 2001
1KNA
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BU of 1kna by Molmil
Chromo domain of HP1 complexed with histone H3 tail containing dimethyllysine 9.
Descriptor: HETEROCHROMATIN PROTEIN 1, METHYLATED Histone H3
Authors:Jacobs, S.A, Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
1KNE
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BU of 1kne by Molmil
Chromo domain of HP1 complexed with histone H3 tail containing trimethyllysine 9
Descriptor: HETEROCHROMATIN PROTEIN 1, Trimethylated Histone H3
Authors:Jacobs, S.A, Khorasanizadeh, S.
Deposit date:2001-12-18
Release date:2002-03-20
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail.
Science, 295, 2002
6D08
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BU of 6d08 by Molmil
Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide
Descriptor: Chromobox protein homolog 1, GLYCEROL, Histone H3.1, ...
Authors:Arora, S, Horne, W.S, Islam, K.
Deposit date:2018-04-10
Release date:2019-04-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
J.Am.Chem.Soc., 141, 2019
3SVM
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BU of 3svm by Molmil
Human MPP8 - human DNMT3AK47me2 peptide
Descriptor: DNA (cytosine-5)-methyltransferase 3A, M-phase phosphoprotein 8
Authors:Chang, Y, Horton, J.R, Zhang, X, Cheng, X.
Deposit date:2011-07-12
Release date:2011-11-30
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a.
Nat Commun, 2, 2011
4QUC
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BU of 4quc by Molmil
Crystal structure of chromodomain of Rhino
Descriptor: RE36324p
Authors:Li, S, Patel, D.J.
Deposit date:2014-07-10
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.502 Å)
Cite:Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Genes Dev., 28, 2014
8SP6
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BU of 8sp6 by Molmil
COMPLEX STRUCTURE OF CDYL2 WITH AN ANTAGONIST
Descriptor: (1s,4s)-bicyclo[2.2.1]heptane, (5R0)FAL(MLZ)(5R5), Chromodomain Y-like protein 2, ...
Authors:Song, X, Beldar, S, Dong, A, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-05-02
Release date:2024-03-13
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:COMPLEX STRUCTURE OF CDYL2 WITH AN ANTAGONIST
To be published
8SII
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BU of 8sii by Molmil
Crystal Structure of CBX7 with compound UNC4976
Descriptor: CALCIUM ION, CHLORIDE ION, Chromobox protein homolog 7, ...
Authors:Song, X, Dong, A, Huang, R, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2023-04-16
Release date:2024-09-04
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Crystal Structure of CBX7 with compound UNC4976
To be published
7M5U
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BU of 7m5u by Molmil
Crystal structure of human MPP8 chromodomain in complex with peptidomimetic ligand UNC5246
Descriptor: M-phase phosphoprotein 8, UNC5246
Authors:Budziszewski, G.R, McGinty, R.K, Waybright, J.M, Norris, J.L, James, L.I.
Deposit date:2021-03-24
Release date:2021-09-01
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex.
Acs Chem.Biol., 16, 2021
6D07
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BU of 6d07 by Molmil
Crystal structure of the complex between human chromobox homolog 1 (CBX1) and H3K9me3 peptide
Descriptor: Chromobox protein homolog 1, GLYCEROL, Histone H3.1
Authors:Arora, S, Horne, W.S, Islam, K.
Deposit date:2018-04-10
Release date:2019-04-10
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions.
J.Am.Chem.Soc., 141, 2019
6ASZ
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BU of 6asz by Molmil
Chromodomain HP1 with Y24F mutation bound to histone H3 peptide containing trimethyl lysine
Descriptor: Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide
Authors:Brustad, E.M, Baril, S.A, Waters, M.L.
Deposit date:2017-08-27
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.518 Å)
Cite:Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.
J. Am. Chem. Soc., 139, 2017
6AT0
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BU of 6at0 by Molmil
Chromodomain HP1 with a p-nitro-L-phenylalanine mutation at position 24 bound to histone H3 peptide containing trimethyl lysine
Descriptor: Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide
Authors:Brustad, E.M, Baril, S.A, Waters, M.L.
Deposit date:2017-08-27
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.285 Å)
Cite:Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis.
J. Am. Chem. Soc., 139, 2017
7N27
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BU of 7n27 by Molmil
Crystal Structure of chromodomain of CDYL in complex with inhibitor UNC6261
Descriptor: Isoform 2 of Chromodomain Y-like protein, SODIUM ION, UNKNOWN ATOM OR ION, ...
Authors:Beldar, S, Dong, A, Loppnau, P, Min, J, Arrowsmith, C.H, Edwards, A.M, Structural Genomics Consortium (SGC)
Deposit date:2021-05-28
Release date:2021-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of chromodomain of CDYL in complex with inhibitor UNC6261
To Be Published
3R93
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BU of 3r93 by Molmil
Crystal structure of the chromo domain of M-phase phosphoprotein 8 bound to H3K9Me3 peptide
Descriptor: H3K9Me3 peptide, M-phase phosphoprotein 8, UNKNOWN ATOM OR ION
Authors:Li, J, Li, Z, Ruan, J, Xu, C, Tong, Y, Pan, P.W, Tempel, W, Crombet, L, Min, J, Zang, J, Structural Genomics Consortium (SGC)
Deposit date:2011-03-24
Release date:2011-04-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.057 Å)
Cite:Structural basis for specific binding of human MPP8 chromodomain to histone H3 methylated at lysine 9.
Plos One, 6, 2011
3TZD
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BU of 3tzd by Molmil
Crystal structure of the complex of Human Chromobox Homolog 3 (CBX3)
Descriptor: Chromobox protein homolog 3, Histone H1.4
Authors:Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC)
Deposit date:2011-09-27
Release date:2012-03-07
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural basis of the chromodomain of Cbx3 bound to methylated peptides from histone h1 and G9a.
Plos One, 7, 2012
4QUF
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BU of 4quf by Molmil
crystal structure of chromodomain of Rhino with H3K9me3
Descriptor: H3(1-15)K9me3 peptide, RE36324p
Authors:Li, S, Patel, D.J.
Deposit date:2014-07-10
Release date:2014-08-20
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.
Genes Dev., 28, 2014
3QO2
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BU of 3qo2 by Molmil
Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9
Descriptor: 1,2-ETHANEDIOL, Histone H3 peptide, M-phase phosphoprotein 8
Authors:Chang, Y, Horton, J.R, Bedford, M.T, Zhang, X, Cheng, X.
Deposit date:2011-02-09
Release date:2011-04-06
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural insights for MPP8 chromodomain interaction with histone H3 lysine 9: potential effect of phosphorylation on methyl-lysine binding.
J.Mol.Biol., 408, 2011
8UMG
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BU of 8umg by Molmil
Chromodomains of human CHD1 complexed with UNC10142
Descriptor: 1-{4-[{2-(azonan-1-yl)-6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}(methyl)amino]piperidin-1-yl}ethan-1-one, CHLORIDE ION, Chromodomain-helicase-DNA-binding protein 1
Authors:Graboski, A.L, Redinbo, M.R.
Deposit date:2023-10-17
Release date:2024-10-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Optimization of a quinazoline-based scaffold against human CHD1
To Be Published

238582

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