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5AFW

Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation

Summary for 5AFW
Entry DOI10.2210/pdb5afw/pdb
DescriptorCHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordshydrolase, lsd1k114me2, androgen receptor, chd1, g9a, prostate cancer, tmprrs2-erg
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus : O14646 O60341
Total number of polymer chains2
Total formula weight22725.66
Authors
Primary citationMetzger, E.,Willmann, D.,Mcmillan, J.,Forne, I.,Metzger, P.,Gerhardt, S.,Petroll, K.,Von Maessenhausen, A.,Urban, S.,Schott, A.,Espejo, A.,Eberlin, A.,Wohlwend, D.,Schule, K.M.,Schleicher, M.,Perner, S.,Bedford, M.T.,Jung, M.,Dengjel, J.,Flaig, R.,Imhof, A.,Einsle, O.,Schule, R.
Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation.
Nat.Struct.Mol.Biol., 23:132-, 2016
Cited by
PubMed: 26751641
DOI: 10.1038/NSMB.3153
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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