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5AFW

Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1polymer17420483.81UniProt (O14646)
Pfam (PF00385)
HOMO SAPIENS (HUMAN)CHD-1, ATP-DEPENDENT HELICASE CHD1, CHROMODOMAIN-HELICASE-D NA-BINDING PROTEIN 1, CHD1
2B
(B)
LYSINE-SPECIFIC HISTONE DEMETHYLASE 1Apolymer121576.91UniProt (O60341)HOMO SAPIENS (HUMAN)BRAF35-HDAC COMPLEX PROTEIN BHC110, FLAVIN-CONTAINING AMINE OXIDASE DOMAIN-CONTAINING PROTEIN 2
3C, D, E, F, G...
(A)
1,2-ETHANEDIOLnon-polymer62.19Chemie (EDO)
4L, M, N
(A)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5O, P
(A, B)
waterwater18.0119Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight22060.7
Non-Polymers*Number of molecules12
Total formula weight665.0
All*Total formula weight22725.7
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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