6AT0
Chromodomain HP1 with a p-nitro-L-phenylalanine mutation at position 24 bound to histone H3 peptide containing trimethyl lysine
Summary for 6AT0
| Entry DOI | 10.2210/pdb6at0/pdb |
| Descriptor | Heterochromatin protein 1, trimethyl lysine histone H3 tail peptide (3 entities in total) |
| Functional Keywords | histone reader, transcription |
| Biological source | Drosophila melanogaster (Fruit fly) More |
| Cellular location | Nucleus, nucleoplasm : P05205 |
| Total number of polymer chains | 2 |
| Total formula weight | 9349.32 |
| Authors | Brustad, E.M.,Baril, S.A.,Waters, M.L. (deposition date: 2017-08-27, release date: 2017-12-06, Last modification date: 2023-10-04) |
| Primary citation | Baril, S.A.,Koenig, A.L.,Krone, M.W.,Albanese, K.I.,He, C.Q.,Lee, G.Y.,Houk, K.N.,Waters, M.L.,Brustad, E.M. Investigation of Trimethyllysine Binding by the HP1 Chromodomain via Unnatural Amino Acid Mutagenesis. J. Am. Chem. Soc., 139:17253-17256, 2017 Cited by PubMed: 29111699DOI: 10.1021/jacs.7b09223 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.285 Å) |
Structure validation
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