6AT0

Chromodomain HP1 with a p-nitro-L-phenylalanine mutation at position 24 bound to histone H3 peptide containing trimethyl lysine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Heterochromatin protein 1	polymer	69	8615.5	1	UniProt (P05205) Pfam (PF00385)	Drosophila melanogaster (Fruit fly)	HP1,Non-histone chromosomal protein C1A9 antigen
2	B (P)	trimethyl lysine histone H3 tail peptide	polymer	6	733.9	1	UniProt (by SIFTS) (P02299)	Drosophila melanogaster
3	C, D (A, P)	water	water		18.0	40	Chemie (HOH)

Sequence modifications

A: 17 - 76 (UniProt: P05205)

PDB	External Database	Details
Met 8	-	initiating methionine
Lys 9	-	expression tag
Lys 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
Ppn 24	Tyr 24	engineered mutation
Met 38	Lys 38	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	9349.3
All*	Total formula weight	9349.3

*Water molecules are not included.