1MIX
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CRYSTAL STRUCTURE OF A FERM DOMAIN OF TALIN
Descriptor:Talin
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
1MIZ
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CRYSTAL STRUCTURE OF AN INTEGRIN BETA3-TALIN CHIMERA
Descriptor:integrin beta3, TALIN
Authors:Garcia-Alvarez, B., de Pereda, J.M., Calderwood, D.A., Ulmer, T.S., Critchley, D., Campbell, I.D., Ginsberg, M.H., Liddington, R.C.
Deposit date:2002-08-23
Release date:2003-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural determinants of integrin recognition by talin
Mol.Cell, 11, 2003
3G9W
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CRYSTAL STRUCTURE OF TALIN2 F2-F3 IN COMPLEX WITH THE INTEGRIN BETA1D CYTOPLASMIC TAIL
Descriptor:Talin-2, Integrin beta-1D, GLYCEROL, ...
Authors:Anthis, N.J., Wegener, K.L., Ye, F., Kim, C., Lowe, E.D., Vakonakis, I., Bate, N., Critchley, D.R., Ginsberg, M.H., Campbell, I.D.
Deposit date:2009-02-15
Release date:2009-10-20
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (2.165 Å)
Cite:The structure of an integrin/talin complex reveals the basis of inside-out signal transduction
Embo J., 28, 2009
3U7D
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CRYSTAL STRUCTURE OF THE KRIT1/CCM1 FERM DOMAIN IN COMPLEX WITH THE HEART OF GLASS (HEG1) CYTOPLASMIC TAIL
Descriptor:Krev interaction trapped protein 1, Protein HEG homolog 1
Authors:Gingras, A.R., Liu, J.J., Ginsberg, M.H., Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2011-10-13
Release date:2012-09-12
Last modified:2013-02-27
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
5D68
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CRYSTAL STRUCTURE OF KRIT1 ARD-FERM
Descriptor:Krev interaction trapped protein 1
Authors:Zhang, R., Li, X., Boggon, T.J.
Deposit date:2015-08-11
Release date:2015-10-21
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.908 Å)
Cite:Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
5XPY
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STRUCTURAL BASIS OF KINDLIN-MEDIATED INTEGRIN RECOGNITION AND ACTIVATION
Descriptor:Fermitin family homolog 2, ACETATE ION, GLYCEROL
Authors:Li, H., Yang, H., Sun, K., Zhang, Z., Yu, C., Wei, Z.
Deposit date:2017-06-05
Release date:2017-07-26
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural basis of kindlin-mediated integrin recognition and activation
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1E5W
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STRUCTURE OF ISOLATED FERM DOMAIN AND FIRST LONG HELIX OF MOESIN
Descriptor:MOESIN
Authors:Edwards, S.D., Keep, N.H.
Deposit date:2000-08-03
Release date:2001-06-27
Last modified:2015-02-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The 2.7 A Crystal Structure of the Activated Ferm Domain of Moesin: An Analysis of Structural Changes on Activation
Biochemistry, 40, 2001
1EF1
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CRYSTAL STRUCTURE OF THE MOESIN FERM DOMAIN/TAIL DOMAIN COMPLEX
Descriptor:MOESIN, SULFATE ION
Authors:Pearson, M.A., Reczek, D., Bretscher, A., Karplus, P.A.
Deposit date:2000-02-04
Release date:2000-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain.
Cell(Cambridge,Mass.), 101, 2000
1GC6
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH INOSITOL-(1,4,5)-TRIPHOSPHATE
Descriptor:RADIXIN, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GC7
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor:RADIXIN
Authors:Hamada, K., Shimizu, T., Matsui, T., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GG3
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CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor:ERYTHROID MEMBRANE PROTEIN 4.1R
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1H4R
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CRYSTAL STRUCTURE OF THE FERM DOMAIN OF MERLIN, THE NEUROFIBROMATOSIS 2 TUMOR SUPPRESSOR PROTEIN.
Descriptor:MERLIN, SULFATE ION
Authors:Cooper, D.R., Kang, B.S., Sheffield, P., Devedjiev, Y., Derewenda, Z.S.
Deposit date:2001-05-14
Release date:2002-01-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
1ISN
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CRYSTAL STRUCTURE OF MERLIN FERM DOMAIN
Descriptor:merlin
Authors:Shimizu, T., Seto, A., Maita, N., Hamada, K., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2001-12-13
Release date:2002-04-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.
J.Biol.Chem., 277, 2002
1J19
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CRYSTAL STRUCTURE OF THE RADXIN FERM DOMAIN COMPLEXED WITH THE ICAM-2 CYTOPLASMIC PEPTIDE
Descriptor:radixin, 16-mer peptide from Intercellular adhesion molecule-2
Authors:Hamada, K., Shimizu, T., Yonemura, S., Tsukita, S., Tsukita, S., Hakoshima, T.
Deposit date:2002-12-02
Release date:2003-03-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex
EMBO J., 22, 2003
1NI2
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STRUCTURE OF THE ACTIVE FERM DOMAIN OF EZRIN
Descriptor:Ezrin
Authors:Smith, W.J., Nassar, N., Bretscher, A.P., Cerione, R.A., Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1SGH
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MOESIN FERM DOMAIN BOUND TO EBP50 C-TERMINAL PEPTIDE
Descriptor:Moesin, Ezrin-radixin-moesin binding phosphoprotein 50
Authors:Finnerty, C.M., Chambers, D., Ingraffea, J., Faber, H.R., Karplus, P.A., Bretscher, A.
Deposit date:2004-02-23
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain
J.Cell.Sci., 117, 2004
2AEH
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FOCAL ADHESION KINASE 1
Descriptor:Focal adhesion kinase 1
Authors:Ceccarelli, D.F., Song, H.K., Poy, F., Schaller, M.D., Eck, M.J.
Deposit date:2005-07-22
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2AL6
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FERM DOMAIN OF FOCAL ADHESION KINASE
Descriptor:Focal adhesion kinase 1
Authors:Ceccarelli, D.F., Song, H.K., Poy, F., Schaller, M.D., Eck, M.J.
Deposit date:2005-08-04
Release date:2005-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure of the FERM Domain of Focal Adhesion Kinase
J.Biol.Chem., 281, 2006
2D10
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-1 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Ezrin-radixin-moesin binding phosphoprotein 50
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D11
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CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN COMPLEXED WITH THE NHERF-2 C-TERMINAL TAIL PEPTIDE
Descriptor:Radixin, Na(+)/H(+) exchange regulatory cofactor NHE-RF2
Authors:Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2005-08-11
Release date:2006-07-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural basis for NHERF recognition by ERM proteins
Structure, 14, 2006
2D2Q
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CRYSTAL STRUCTURE OF THE DIMERIZED RADIXIN FERM DOMAIN
Descriptor:Radixin
Authors:Kitano, K., Yusa, F., Hakoshima, T.
Deposit date:2005-09-15
Release date:2006-04-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of dimerized radixin FERM domain suggests a novel masking motif in C-terminal residues 295-304
ACTA CRYSTALLOGR.,SECT.F, 62, 2006
2EMS
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CRYSTAL STRUCTURE ANALYSIS OF THE RADIXIN FERM DOMAIN COMPLEXED WITH ADHESION MOLECULE CD43
Descriptor:Radixin, Leukosialin
Authors:Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of the cytoplasmic tail of adhesion molecule CD43 and its binding to ERM proteins
J.Mol.Biol., 381, 2008
2EMT
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CRYSTAL STRUCTURE ANALYSIS OF THE RADIXIN FERM DOMAIN COMPLEXED WITH ADHESION MOLECULE PSGL-1
Descriptor:Radixin, P-selectin glycoprotein ligand 1
Authors:Takai, Y., Kitano, K., Terawaki, S., Maesaki, R., Hakoshima, T.
Deposit date:2007-03-28
Release date:2008-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of PSGL-1 binding to ERM proteins
Genes Cells, 12, 2007
2HE7
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FERM DOMAIN OF EPB41L3 (DAL-1)
Descriptor:Band 4.1-like protein 3
Authors:Hallberg, B.M., Busam, R.D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Schiavone, L.H., Johansson, I., Hogbom, M., Karlberg, T., Kotenyova, T., Nilvebrandt, J., Norberg, P., Stenmark, P., Nordlund, P., Nilsson-ehle, P., Nyman, T., Ogg, D., Sagemark, J., Sundstrom, M., Uppenberg, J., Van den berg, S., Weigelt, J., Persson, C., Thorsell, A.G., Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of tumor suppressor in lung cancer 1 (TSLC1) binding to differentially expressed in adenocarcinoma of the lung (DAL-1/4.1B).
J.Biol.Chem., 286, 2011
2I1J
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MOESIN FROM SPODOPTERA FRUGIPERDA AT 2.1 ANGSTROMS RESOLUTION
Descriptor:Moesin, CHLORIDE ION, UREA, ...
Authors:Li, Q., Nance, M.R., Tesmer, J.J.G.
Deposit date:2006-08-14
Release date:2006-12-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain.
J.Mol.Biol., 365, 2007
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