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6VPD
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BU of 6vpd by Molmil
Crystal structure of Trgpx in apo form
Descriptor: Glutathione peroxidase
Authors:Adriani, P.P, De Oliveira, G.S, Paiva, F.C.R, Dias, M.V.B, Chambergo, F.S.
Deposit date:2020-02-03
Release date:2020-12-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:Structural and functional characterization of the glutathione peroxidase-like thioredoxin peroxidase from the fungus Trichoderma reesei.
Int.J.Biol.Macromol., 167, 2020
6ELW
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BU of 6elw by Molmil
High resolution structure of selenocysteine containing human GPX4
Descriptor: CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
Authors:Kalms, J, Borchert, A, Kuhn, H, Scheerer, P.
Deposit date:2017-09-29
Release date:2018-06-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction.
Biochim. Biophys. Acta, 1863, 2018
3KIJ
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BU of 3kij by Molmil
Crystal structure of the human PDI-peroxidase
Descriptor: Probable glutathione peroxidase 8, SULFATE ION
Authors:Nguyen, D.V, Ruddock, L.W.
Deposit date:2009-11-02
Release date:2011-01-12
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Two Endoplasmic Reticulum PDI Peroxidases Increase the Efficiency of the Use of Peroxide during Disulfide Bond Formation.
J.Mol.Biol., 406, 2011
7FC2
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BU of 7fc2 by Molmil
Crystal Structure of GPX6
Descriptor: Glutathione peroxidase 6, SULFATE ION
Authors:Sun, J.
Deposit date:2021-07-13
Release date:2022-07-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of GPX6
To Be Published
5L71
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BU of 5l71 by Molmil
Crystal structure of mouse phospholipid hydroperoxide glutathione peroxidase 4 (GPx4)
Descriptor: 1,2-ETHANEDIOL, Phospholipid hydroperoxide glutathione peroxidase, mitochondrial
Authors:Janowski, R, Scanu, S, Madl, T, Niessing, D.
Deposit date:2016-06-01
Release date:2016-10-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4.
Acta Crystallogr.,Sect.F, 72, 2016
2F8A
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BU of 2f8a by Molmil
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
Descriptor: Glutathione peroxidase 1, MALONIC ACID
Authors:Kavanagh, K.L, Johansson, C, Smee, C, Gileadi, O, von Delft, F, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2005-12-02
Release date:2005-12-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
1GP1
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BU of 1gp1 by Molmil
THE REFINED STRUCTURE OF THE SELENOENZYME GLUTATHIONE PEROXIDASE AT 0.2-NM RESOLUTION
Descriptor: GLUTATHIONE PEROXIDASE
Authors:Epp, O, Ladenstein, R.
Deposit date:1985-06-11
Release date:1985-11-08
Last modified:2023-07-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution.
Eur.J.Biochem., 133, 1983
8Q8J
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BU of 8q8j by Molmil
Crystal structure of human GPX4-R152H
Descriptor: Glutathione peroxidase
Authors:Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G.
Deposit date:2023-08-18
Release date:2024-08-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human GPX4-R152H
To Be Published
8Q8N
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BU of 8q8n by Molmil
Crystal structure of human GPX4-U46C-I129S-L130S
Descriptor: Phospholipid hydroperoxide glutathione peroxidase
Authors:Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G.
Deposit date:2023-08-18
Release date:2024-08-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
6HN3
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wildtype form (apo) of human GPX4 with Se-Cys46
Descriptor: CHLORIDE ION, ETHANOL, GLYCEROL, ...
Authors:Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, J, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S.
Deposit date:2018-09-13
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.01 Å)
Cite:Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
6HKQ
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BU of 6hkq by Molmil
Human GPX4 in complex with covalent Inhibitor ML162 (S enantiomer)
Descriptor: (2~{S})-2-[2-chloranylethanoyl-(3-chloranyl-4-methoxy-phenyl)amino]-~{N}-(2-phenylethyl)-2-thiophen-2-yl-ethanamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ...
Authors:Hillig, R.C, Moosmayer, D, Hilpmann, A, Hoffmann, L, Schnirch, L, Eaton, J.K, Badock, V, Gradl, S.
Deposit date:2018-09-07
Release date:2020-04-01
Last modified:2022-12-07
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.
Acta Crystallogr D Struct Biol, 77, 2021
2I3Y
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BU of 2i3y by Molmil
Crystal structure of human glutathione peroxidase 5
Descriptor: 1,2-ETHANEDIOL, Epididymal secretory glutathione peroxidase
Authors:Kavanagh, K.L, Johansson, C, Rojkova, A, Umeano, C, Bunkoczi, G, Gileadi, O, von Delft, F, Weigelt, J, Arrowsmith, C, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-08-21
Release date:2006-09-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human glutathione peroxidase 5
To be published
5H5R
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BU of 5h5r by Molmil
Crystal structure of human GPX4 in complex with GXpep-2
Descriptor: GLYCEROL, GXpep-2, Phospholipid hydroperoxide glutathione peroxidase, ...
Authors:Sogabe, S, Kadotani, A, Lane, W, Snell, G.
Deposit date:2016-11-09
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
5H5Q
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BU of 5h5q by Molmil
Crystal structure of human GPX4 in complex with GXpep-1
Descriptor: GLYCEROL, GXpep-1, Phospholipid hydroperoxide glutathione peroxidase, ...
Authors:Sogabe, S, Kadotani, A, Lane, W, Snell, G.
Deposit date:2016-11-09
Release date:2016-12-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
5H5S
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BU of 5h5s by Molmil
Crystal structure of human GPX4 in complex with GXpep-3
Descriptor: GLYCEROL, GXpep-3, Phospholipid hydroperoxide glutathione peroxidase, ...
Authors:Sogabe, S, Kadotani, A, Lane, W, Snell, G.
Deposit date:2016-11-09
Release date:2016-12-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of GPX4 inhibitory peptides from random peptide T7 phage display and subsequent structural analysis
Biochem. Biophys. Res. Commun., 482, 2017
2HE3
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BU of 2he3 by Molmil
Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
Descriptor: CHLORIDE ION, Glutathione peroxidase 2
Authors:Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-06-21
Release date:2006-07-25
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the selenocysteine to cysteine mutant of human glutathionine peroxidase 2 (GPX2)
To be Published
2GS3
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BU of 2gs3 by Molmil
Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)
Descriptor: CHLORIDE ION, Phospholipid hydroperoxide glutathione peroxidase
Authors:Johansson, C, Kavanagh, K.L, Rojkova, A, Gileadi, O, von Delft, F, Arrowsmith, C, Weigelt, J, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2006-04-25
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 4(GPX4)
To be Published
3DWV
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BU of 3dwv by Molmil
Glutathione peroxidase-type tryparedoxin peroxidase, oxidized form
Descriptor: Glutathione peroxidase-like protein
Authors:Tews, I, Sinning, I, Krauth-Siegel, L.
Deposit date:2008-07-23
Release date:2008-08-05
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase.
J.Biol.Chem., 283, 2008
3CMI
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BU of 3cmi by Molmil
Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae
Descriptor: Peroxiredoxin HYR1
Authors:Zhang, W.J.Z, He, Y.X, Yu, J, Zhou, C.Z.
Deposit date:2008-03-21
Release date:2008-09-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Crystal structure of glutathione-dependent phospholipid peroxidase Hyr1 from the yeast Saccharomyces cerevisiae
Proteins, 73, 2008
2OBI
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BU of 2obi by Molmil
Crystal structure of the Selenocysteine to Cysteine Mutant of human phospholipid hydroperoxide glutathione peroxidase (GPx4)
Descriptor: Phospholipid hydroperoxide glutathione peroxidase (GPX4)
Authors:Scheerer, P, Krauss, N, Hoehne, W.
Deposit date:2006-12-19
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for catalytic activity and enzyme polymerization of phospholipid hydroperoxide glutathione peroxidase-4 (GPx4).
Biochemistry, 46, 2007
3CYN
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BU of 3cyn by Molmil
The structure of human GPX8
Descriptor: GLYCEROL, Probable glutathione peroxidase 8, SULFATE ION
Authors:Kavanagh, K.L, Johansson, C, Yue, W.W, Kochan, G, Pike, A.C.W, Murray, J, Roos, A.K, Filippakopoulos, P, von Delft, F, Arrowsmith, C.H, Wikstrom, M, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2008-04-25
Release date:2008-08-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of human GPX8
To be Published
3E0U
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BU of 3e0u by Molmil
Crystal structure of T. cruzi GPX1
Descriptor: AMMONIUM ION, GLYCEROL, Glutathione peroxidase
Authors:Patel, S.H, Hussain, S, Harris, R, Driscoll, P, Djordjevic, S.
Deposit date:2008-08-01
Release date:2009-08-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I).
Biochem.J., 425, 2010
2P31
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BU of 2p31 by Molmil
Crystal structure of human glutathione peroxidase 7
Descriptor: CHLORIDE ION, Glutathione peroxidase 7
Authors:Kavanagh, K.L, Johansson, C, Papagrigoriou, E, Kochan, G, Umeano, C, Gileadi, O, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-03-08
Release date:2007-03-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of human glutathione peroxidase 7
To be Published
2P5R
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BU of 2p5r by Molmil
Crystal structure of the poplar glutathione peroxidase 5 in the oxidized form
Descriptor: CALCIUM ION, Glutathione peroxidase 5
Authors:Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
Deposit date:2007-03-16
Release date:2007-07-24
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007
2P5Q
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BU of 2p5q by Molmil
Crystal structure of the poplar glutathione peroxidase 5 in the reduced form
Descriptor: ACETATE ION, CADMIUM ION, Glutathione peroxidase 5
Authors:Koh, C.S, Didierjean, C, Navrot, N, Panjikar, S, Mulliert, G, Rouhier, N, Jacquot, J.-P, Aubry, A, Shawkataly, O, Corbier, C.
Deposit date:2007-03-16
Release date:2007-07-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of a Poplar Thioredoxin Peroxidase that Exhibits the Structure of Glutathione Peroxidases: Insights into Redox-driven Conformational Changes.
J.Mol.Biol., 370, 2007

 

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