6HN3

wildtype form (apo) of human GPX4 with Se-Cys46

Summary for 6HN3

• Entry DOI: 10.2210/pdb6hn3/pdb
• Related: 6HKQ
• Descriptor: Phospholipid hydroperoxide glutathione peroxidase, CHLORIDE ION, ETHANOL, ... (5 entities in total)
• Functional Keywords: anti-oxidatve defense system, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 20637.43

Authors

Hillig, R.C.,Moosmayer, D.,Hilpmann, A.,Hoffmann, J.,Schnirch, L.,Eaton, J.K.,Badock, V.,Gradl, S. (deposition date: 2018-09-13, release date: 2020-04-01, Last modification date: 2024-01-24)

• Primary citation: Moosmayer, D.,Hilpmann, A.,Hoffmann, J.,Schnirch, L.,Zimmermann, K.,Badock, V.,Furst, L.,Eaton, J.K.,Viswanathan, V.S.,Schreiber, S.L.,Gradl, S.,Hillig, R.C.; Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162.; Acta Crystallogr D Struct Biol, 77:237-248, 2021; PubMed: 33559612; DOI: 10.1107/S2059798320016125

Experimental method

X-RAY DIFFRACTION (1.01 Å)