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2EDD
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BU of 2edd by Molmil
Solution structure of the fifth fibronectin type III domain of human Netrin receptor DCC
Descriptor: Netrin receptor DCC
Authors:Tochio, N, Koshiba, S, Tomizawa, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2008-03-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the fifth fibronectin type III domain of human Netrin receptor DCC
To be Published
2EDE
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BU of 2ede by Molmil
Solution structure of the sixth fibronectin type III domain of human Netrin receptor DCC
Descriptor: Netrin receptor DCC
Authors:Tochio, N, Koshiba, S, Tomizawa, T, Yoneyama, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-14
Release date:2008-03-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the sixth fibronectin type III domain of human Netrin receptor DCC
To be Published
2EE2
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BU of 2ee2 by Molmil
Solution structures of the fn3 domain of human contactin 1
Descriptor: Contactin-1
Authors:Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the fn3 domain of human contactin 1
To be Published
2CRM
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BU of 2crm by Molmil
Solution structure of the forth FNIII domain of human
Descriptor: Fibronectin type-III domain containing protein 3a
Authors:Izumi, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the forth FNIII domain of human
To be published
2CUM
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BU of 2cum by Molmil
The solution structure of the 33rd fibronectin type III domain of human Tenascin-X
Descriptor: Tenascin-X
Authors:Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-26
Release date:2005-11-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The solution structure of the 33rd fibronectin type III domain of human Tenascin-X
To be Published
2DM4
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BU of 2dm4 by Molmil
Solution structure of the second fn3 domain of human sorLA/LR11
Descriptor: Sortilin-related receptor
Authors:Nagashima, T, Kurosaki, C, Yoshida, M, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second fn3 domain of human sorLA/LR11
To be Published
2CRZ
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BU of 2crz by Molmil
Solution structure of the fifth FNIII domain of human fibronectin type III domain containing protein 3a
Descriptor: Fibronectin type-III domain containing protein 3a
Authors:Kurosaki, C, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the fifth FNIII domain of human fibronectin type III domain containing protein 3a
To be published
2CUH
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BU of 2cuh by Molmil
Solution structure of the 31st fibronectin type III domain of the human tenascin X
Descriptor: Tenascin-X
Authors:Ohnishi, S, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-26
Release date:2005-11-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 31st fibronectin type III domain of the human tenascin X
To be Published
2CUI
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BU of 2cui by Molmil
Solution structure of the 31st fibronectin type III domain of the human tenascin X
Descriptor: Tenascin-X
Authors:Ohnishi, S, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-26
Release date:2005-11-26
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 31st fibronectin type III domain of the human tenascin X
To be Published
2DLH
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BU of 2dlh by Molmil
Solution structure of the second fn3 domain of human receptor-type tyrosine-protein phosphatase delta
Descriptor: Receptor-type tyrosine-protein phosphatase delta
Authors:Seimiya, K, Hayashi, F, Yoshida, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-18
Release date:2006-10-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second fn3 domain of human receptor-type tyrosine-protein phosphatase delta
To be published
2DOC
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BU of 2doc by Molmil
Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2
Descriptor: Neural cell adhesion molecule 2
Authors:Yoneyama, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-28
Release date:2006-10-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the Fibronectin type-III domain of human Neural cell adhesion molecule 2
To be Published
2DN7
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BU of 2dn7 by Molmil
Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F
Descriptor: Receptor-type tyrosine-protein phosphatase F
Authors:Sato, M, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-25
Release date:2006-10-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the 6th fn3 domain of human receptor-type tyrosine-protein phosphatase F
To be Published
7NWL
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BU of 7nwl by Molmil
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ...
Authors:Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N.
Deposit date:2021-03-17
Release date:2021-06-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand.
Sci Adv, 7, 2021
8G4L
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BU of 8g4l by Molmil
Cryo-EM structure of the human cardiac myosin filament
Descriptor: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ...
Authors:Dutta, D, Nguyen, V, Padron, R, Craig, R.
Deposit date:2023-02-10
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Cryo-EM structure of the human cardiac myosin filament.
Nature, 623, 2023
8BXR
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BU of 8bxr by Molmil
Titin FnIII-domain I109-I111 (I/A4-A/A6) from the MIR region
Descriptor: 1,2-ETHANEDIOL, Titin
Authors:Mayans, O, Fleming, J.R, Williams, R.
Deposit date:2022-12-09
Release date:2023-02-15
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis.
Biomedicines, 11, 2023
4URT
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BU of 4urt by Molmil
The crystal structure of a fragment of netrin-1 in complex with FN5- FN6 of DCC
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Finci, L.I, Krueger, N, Sun, X, Zhang, J, Chegkazi, M, Wu, Y, Schenk, G, Mertens, H.D.T, Svergun, D.I, Zhang, Y, Wang, J.-h, Meijers, R.
Deposit date:2014-07-02
Release date:2014-09-10
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The Crystal Structure of Netrin-1 in Complex with Dcc Reveals the Bi-Functionality of Netrin-1 as a Guidance Cue
Neuron, 83, 2014
4M4R
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BU of 4m4r by Molmil
Epha4 ectodomain complex with ephrin a5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ephrin type-A receptor 4, ...
Authors:Xu, K, Tsvetkova-Robev, D, Xu, Y, Goldgur, Y, Chan, Y.-P, Himanen, J.P, Nikolov, D.B.
Deposit date:2013-08-07
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Insights into Eph receptor tyrosine kinase activation from crystal structures of the EphA4 ectodomain and its complex with ephrin-A5.
Proc.Natl.Acad.Sci.USA, 110, 2013
2AEW
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BU of 2aew by Molmil
A model for growth hormone receptor activation based on subunit rotation within a receptor dimer
Descriptor: Growth hormone receptor
Authors:Adams, J.J, McKinstry, W.J, Parker, M.W, Waters, M.J.
Deposit date:2005-07-24
Release date:2005-11-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Model for growth hormone receptor activation based on subunit rotation within a receptor dimer.
Nat.Struct.Mol.Biol., 12, 2005
1HWH
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BU of 1hwh by Molmil
1:1 COMPLEX OF HUMAN GROWTH HORMONE MUTANT G120R WITH ITS SOLUBLE BINDING PROTEIN
Descriptor: GROWTH HORMONE, GROWTH HORMONE BINDING PROTEIN
Authors:Sundstrom, S.M, Lundqvist, T.
Deposit date:1996-11-13
Release date:1997-11-19
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9 A resolution.
J.Biol.Chem., 271, 1996
4Y5Y
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BU of 4y5y by Molmil
Diabody 330 complex with EpoR
Descriptor: Erythropoietin receptor, GLYCEROL, diabody 330 VH domain, ...
Authors:Moraga, I, Guo, F, Ozkan, E, Jude, K.M, Garcia, K.C.
Deposit date:2015-02-12
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands.
Cell, 160, 2015
6IAA
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BU of 6iaa by Molmil
hRobo2 ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Barak, R, Isupov, N.M, Opatowsky, Y.
Deposit date:2018-11-26
Release date:2019-03-13
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural Principles in Robo Activation and Auto-inhibition.
Cell, 177, 2019
7OPB
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BU of 7opb by Molmil
IL7R in complex with an antagonist
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ...
Authors:Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N.
Deposit date:2021-05-31
Release date:2022-05-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.144 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
3HHR
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BU of 3hhr by Molmil
HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX
Descriptor: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
Authors:De Vos, A.M, Ultsch, M, Kossiakoff, A.A.
Deposit date:1993-12-30
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.
Science, 255, 1992
4GH7
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BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
Descriptor: Fibronectin, Neutrophil gelatinase-associated lipocalin
Authors:Schiefner, A, Gebauer, M, Skerra, A.
Deposit date:2012-08-07
Release date:2012-12-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
2X11
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BU of 2x11 by Molmil
Crystal structure of the complete EphA2 ectodomain in complex with ephrin A5 receptor binding domain
Descriptor: EPHRIN TYPE-A RECEPTOR 2, EPHRIN-A5
Authors:Seiradake, E, Harlos, K, Sutton, G, Aricescu, A.R, Jones, E.Y.
Deposit date:2009-12-21
Release date:2010-03-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (4.83 Å)
Cite:An Extracellular Steric Seeding Mechanism for Eph-Ephrin Signalling Platform Assembly
Nat.Struct.Mol.Biol., 17, 2010

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