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1G41
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BU of 1g41 by Molmil
CRYSTAL STRUCTURE OF HSLU HAEMOPHILUS INFLUENZAE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, HEAT SHOCK PROTEIN HSLU, SULFATE ION
Authors:Trame, C.B, McKay, D.B.
Deposit date:2000-10-25
Release date:2000-11-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of Haemophilus influenzae HslU protein in crystals with one-dimensional disorder twinning.
Acta Crystallogr.,Sect.D, 57, 2001
1DO0
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BU of 1do0 by Molmil
ORTHORHOMBIC CRYSTAL FORM OF HEAT SHOCK LOCUS U (HSLU) FROM ESCHERICHIA COLI
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PROTEIN (HEAT SHOCK LOCUS U), ...
Authors:Bochtler, M, Hartmann, C, Song, H.K, Bourenkov, G.P, Bartunik, H.D.
Deposit date:1999-12-18
Release date:2000-02-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of HsIU and the ATP-dependent protease HsIU-HsIV.
Nature, 403, 2000
1G4A
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BU of 1g4a by Molmil
CRYSTAL STRUCTURES OF THE HSLVU PEPTIDASE-ATPASE COMPLEX REVEAL AN ATP-DEPENDENT PROTEOLYSIS MECHANISM
Descriptor: 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HSL PROTEASE ATP-BINDING SUBUNIT HSLU, ATP-DEPENDENT PROTEASE HSLV
Authors:Wang, J, Song, J.J, Franklin, M.C, Kamtekar, S, Im, Y.J, Rho, S.H, Seong, I.S, Lee, C.S, Chung, C.H, Eom, S.H.
Deposit date:2000-10-26
Release date:2001-02-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism.
Structure, 9, 2001
6P11
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BU of 6p11 by Molmil
Structure of spastin AAA domain (T692A mutant) in complex with JNJ-7706621 inhibitor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Drosophila melanogaster Spastin AAA domain, ...
Authors:Pisa, R, Cupido, T, Kapoor, T.M.
Deposit date:2019-05-17
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Cell Chem Biol, 26, 2019
6P10
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BU of 6p10 by Molmil
Structure of spastin AAA domain (N527C mutant) in complex with JNJ-7706621 inhibitor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzenesulfonamide, Drosophila melanogaster Spastin AAA domain, ...
Authors:Pisa, R, Cupido, T, Kapoor, T.M.
Deposit date:2019-05-17
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Cell Chem Biol, 26, 2019
6PE0
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BU of 6pe0 by Molmil
Msp1 (E214Q)-substrate complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Membrane-spanning ATPase-like protein, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
6P12
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BU of 6p12 by Molmil
Structure of spastin AAA domain (wild-type) in complex with diaminotriazole-based inhibitor
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, Drosophila melanogaster Spastin AAA domain, ...
Authors:Pisa, R, Cupido, T, Kapoor, T.M.
Deposit date:2019-05-17
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94131851 Å)
Cite:Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Cell Chem Biol, 26, 2019
6P8V
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BU of 6p8v by Molmil
Structure of E. coli MS115-1 HORMA:CdnC:Trip13 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATPase, AAA family, ...
Authors:Ye, Q, Corbett, K.D.
Deposit date:2019-06-08
Release date:2019-12-25
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.64 Å)
Cite:HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity.
Mol.Cell, 77, 2020
6P07
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BU of 6p07 by Molmil
Spastin hexamer in complex with substrate
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sandate, C.R, Szyk, A, Zehr, E, Roll-Mecak, A, Lander, G.C.
Deposit date:2019-05-16
Release date:2019-06-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:An allosteric network in spastin couples multiple activities required for microtubule severing.
Nat.Struct.Mol.Biol., 26, 2019
6P14
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BU of 6p14 by Molmil
Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form B)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, ACETATE ION, ...
Authors:Pisa, R, Cupido, T, Kapoor, T.M.
Deposit date:2019-05-17
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93001127 Å)
Cite:Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Cell Chem Biol, 26, 2019
6PDY
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BU of 6pdy by Molmil
Msp1-substrate complex in open conformation
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Wang, L, Myasnikov, A, Pan, X, Walter, P.
Deposit date:2019-06-19
Release date:2020-02-12
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the AAA protein Msp1 reveals mechanism of mislocalized membrane protein extraction.
Elife, 9, 2020
6P13
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BU of 6p13 by Molmil
Structure of spastin AAA domain (T692A mutant) in complex with a diaminotriazole-based inhibitor (crystal form A)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-{[5-amino-1-(2-fluoro-6-methoxybenzene-1-carbonyl)-1H-1,2,4-triazol-3-yl]amino}-N-methylbenzamide, SULFATE ION, ...
Authors:Pisa, R, Cupido, T, Kapoor, T.M.
Deposit date:2019-05-17
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Analyzing Resistance to Design Selective Chemical Inhibitors for AAA Proteins.
Cell Chem Biol, 26, 2019
5JPQ
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BU of 5jpq by Molmil
Cryo-EM structure of the 90S pre-ribosome
Descriptor: 18S ribosomal RNA, Bms1, Emg1, ...
Authors:Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R.
Deposit date:2016-05-04
Release date:2016-07-27
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome.
Cell, 166, 2016
8VLS
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BU of 8vls by Molmil
Structure of VCP in complex with an ATPase activator (D2 domains only, dodecameric form)
Descriptor: (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, Transitional endoplasmic reticulum ATPase
Authors:Jones, N.H, Urnivicius, L, Kapoor, T.M.
Deposit date:2024-01-12
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VOV
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BU of 8vov by Molmil
Structure of VCP in complex with an ATPase activator and ADP (D2 domains only, hexameric form)
Descriptor: (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Jones, N.H, Urnivicius, L, Kapoor, T.M.
Deposit date:2024-01-16
Release date:2024-06-19
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry.
Proc.Natl.Acad.Sci.USA, 121, 2024
7BP9
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BU of 7bp9 by Molmil
Human AAA+ ATPase VCP mutant - T76E, ADP-bound form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Yang, C, Zhang, H.
Deposit date:2020-03-21
Release date:2021-03-31
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BPB
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BU of 7bpb by Molmil
Human AAA+ ATPase VCP mutant - T76E, AMP-PNP bound form, Conformation I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
Authors:Yang, C, Zhang, H.
Deposit date:2020-03-22
Release date:2021-03-31
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BP8
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BU of 7bp8 by Molmil
Human AAA+ ATPase VCP mutant - T76A, ADP-bound form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Yang, C, Zhang, H.
Deposit date:2020-03-21
Release date:2021-03-31
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
7BPA
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BU of 7bpa by Molmil
Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I
Descriptor: ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase
Authors:Yang, C, Zhang, H.
Deposit date:2020-03-21
Release date:2021-03-31
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.
Cell Death Differ., 2022
6Z1E
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BU of 6z1e by Molmil
Crystal structure of the AAA domain of Rubisco Activase from Nostoc sp. (strain PCC 7120)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Ribulose bisphosphate carboxylase/oxygenase activase
Authors:Popilka, L, Bracher, A.
Deposit date:2020-05-13
Release date:2020-09-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.454 Å)
Cite:Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.
Cell, 183, 2020
5KWA
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BU of 5kwa by Molmil
complete structure of the Mycobacterium tuberculosis proteasomal ATPase Mpa
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Proteasome-associated ATPase
Authors:Wang, T, WU, Y.J.
Deposit date:2016-07-17
Release date:2017-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mycobacterium tuberculosis proteasomal ATPase Mpa has a beta-grasp domain that hinders docking with the proteasome core protease
Mol. Microbiol., 105, 2017
7CTF
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BU of 7ctf by Molmil
Human origin recognition complex 1-5 State II
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
Authors:Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
Deposit date:2020-08-18
Release date:2021-01-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
7CTG
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BU of 7ctg by Molmil
Human Origin Recognition Complex, ORC1-5 State I
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 1, Origin recognition complex subunit 2, ...
Authors:Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N.
Deposit date:2020-08-18
Release date:2021-01-06
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insight into the assembly and conformational activation of human origin recognition complex.
Cell Discov, 6, 2020
5KIW
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BU of 5kiw by Molmil
p97 ND1-L198W in complex with VIMP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Selenoprotein S, ...
Authors:Tang, W.K, Xia, D.
Deposit date:2016-06-17
Release date:2018-03-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Structural basis for nucleotide-modulated p97 association with the ER membrane.
Cell Discov, 3, 2017
8XON
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BU of 8xon by Molmil
Cryo-EM structure of the ClpC1:ClpP1P2 degradation complex in Streptomyces hawaiiensis
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent Clp protease proteolytic subunit, ...
Authors:Xu, X, Long, F.
Deposit date:2024-01-01
Release date:2024-03-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Structural insights into the Clp protein degradation machinery.
Mbio, 15, 2024

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