7BPA

Human AAA+ ATPase VCP mutant - T76A, AMP-PNP-bound form, Conformation I

Summary for 7BPA

• Entry DOI: 10.2210/pdb7bpa/pdb
• Related: 7BP8 7BP9
• EMDB information: 30147 30148 30149
• Descriptor: Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER (3 entities in total)
• Functional Keywords: complex, atpase, unfoldase, protein transportation, cell cycle
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 542041.12

Authors

Yang, C.,Zhang, H. (deposition date: 2020-03-21, release date: 2021-03-31, Last modification date: 2022-04-27)

• Primary citation: Zhu, K.,Cai, Y.,Si, X.,Ye, Z.,Gao, Y.,Liu, C.,Wang, R.,Ma, Z.,Zhu, H.,Zhang, L.,Li, S.,Zhang, H.,Yue, J.; The phosphorylation and dephosphorylation switch of VCP/p97 regulates the architecture of centrosome and spindle.; Cell Death Differ., 2022; PubMed: 35430615; DOI: 10.1038/s41418-022-01000-4

Experimental method

ELECTRON MICROSCOPY (3.3 Å)