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2JL9
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BU of 2jl9 by Molmil
Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase
Descriptor: RNA-DIRECTED RNA POLYMERASE
Authors:Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M.
Deposit date:2008-09-05
Release date:2008-11-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase.
Nucleic Acids Res., 36, 2008
8IIC
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BU of 8iic by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta40 mutant (residues 41-546)
Descriptor: Polymerase polyprotein
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
8IIB
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BU of 8iib by Molmil
Crystal structure of Israeli acute paralysis virus RNA-dependent RNA polymerase delta85 mutant (residues 86-546)
Descriptor: CADMIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Fang, X, Lu, G, Hou, C, Gong, P.
Deposit date:2023-02-24
Release date:2023-06-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Unusual substructure conformations observed in crystal structures of a dicistrovirus RNA-dependent RNA polymerase suggest contribution of the N-terminal extension in proper folding.
Virol Sin, 38, 2023
3OLB
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BU of 3olb by Molmil
Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp
Descriptor: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, Polymerase, ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OLA
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BU of 3ola by Molmil
Poliovirus polymerase elongation complex with 2'-deoxy-CTP
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3N6M
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BU of 3n6m by Molmil
Crystal structure of EV71 RdRp in complex with GTP
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase
Authors:Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H.
Deposit date:2010-05-26
Release date:2011-06-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
3NKY
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BU of 3nky by Molmil
Structure of a mutant P44S of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Descriptor: 3D polymerase, MAGNESIUM ION
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-21
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
3NMA
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BU of 3nma by Molmil
Mutant P169S of Foot-and-mouth disease Virus RNA dependent RNA-polymerase
Descriptor: 5'-R(*GP*GP*C)-3', 5'-R(P*CP*C)-3', Genome polyprotein, ...
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-22
Release date:2011-05-25
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
3OL8
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BU of 3ol8 by Molmil
Poliovirus polymerase elongation complex with CTP-Mn
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OL6
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BU of 3ol6 by Molmil
Poliovirus polymerase elongation complex
Descriptor: ISOPROPYL ALCOHOL, Polymerase, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*CP*GP*GP*AP*AP*A)-3'), ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3N6N
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BU of 3n6n by Molmil
crystal structure of EV71 RdRp in complex with Br-UTP
Descriptor: 5-bromouridine 5'-(tetrahydrogen triphosphate), NICKEL (II) ION, RNA-dependent RNA polymerase
Authors:Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H.
Deposit date:2010-05-26
Release date:2011-06-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
3NAH
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BU of 3nah by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
Descriptor: RNA dependent RNA polymerase, SULFATE ION
Authors:Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S.
Deposit date:2010-06-02
Release date:2011-06-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
3NL0
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BU of 3nl0 by Molmil
Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
Descriptor: 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ...
Authors:Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
Deposit date:2010-06-21
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
3N6L
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BU of 3n6l by Molmil
The crystal structure of RNA-dependent RNA polymerase of EV71 virus
Descriptor: NICKEL (II) ION, RNA-dependent RNA polymerase
Authors:Wu, Y, Rao, Z.H.
Deposit date:2010-05-26
Release date:2011-06-15
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010
3NAI
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BU of 3nai by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
Descriptor: 5-FLUOROURACIL, GLYCEROL, MAGNESIUM ION, ...
Authors:Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S.
Deposit date:2010-06-02
Release date:2011-06-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
3OL9
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BU of 3ol9 by Molmil
Poliovirus polymerase elongation complex with 3'-deoxy-CTP
Descriptor: ISOPROPYL ALCOHOL, PYROPHOSPHATE 2-, Polymerase, ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OL7
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BU of 3ol7 by Molmil
Poliovirus polymerase elongation complex with CTP
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Gong, P, Peersen, O.B.
Deposit date:2010-08-25
Release date:2010-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3QID
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BU of 3qid by Molmil
Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
Descriptor: GLYCEROL, MANGANESE (III) ION, RNA dependent RNA polymerase, ...
Authors:Kim, K.H, Intekhab, A, Lee, J.H.
Deposit date:2011-01-27
Release date:2011-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase.
J.Gen.Virol., 92, 2011
1SH2
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BU of 1sh2 by Molmil
Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic)
Descriptor: RNA Polymerase
Authors:Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F.
Deposit date:2004-02-24
Release date:2004-03-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
1RA7
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BU of 1ra7 by Molmil
Poliovirus Polymerase with GTP
Descriptor: ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RAJ
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BU of 1raj by Molmil
Poliovirus Polymerase with a 68 residue N-terminal truncation
Descriptor: Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1U09
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BU of 1u09 by Molmil
Footand Mouth Disease Virus RNA-dependent RNA polymerase
Descriptor: polyprotein
Authors:Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N.
Deposit date:2004-07-13
Release date:2004-08-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA
J.Biol.Chem., 279, 2004
1RA6
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BU of 1ra6 by Molmil
Poliovirus Polymerase Full Length Apo Structure
Descriptor: ACETIC ACID, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RDR
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BU of 1rdr by Molmil
POLIOVIRUS 3D POLYMERASE
Descriptor: CALCIUM ION, POLIOVIRUS 3D POLYMERASE
Authors:Hansen, J, Long, A, Schultz, S.
Deposit date:1998-04-28
Release date:1998-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RNA-dependent RNA polymerase of poliovirus.
Structure, 5, 1997
1SH0
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BU of 1sh0 by Molmil
Crystal Structure of Norwalk Virus Polymerase (Triclinic)
Descriptor: RNA Polymerase
Authors:Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F.
Deposit date:2004-02-24
Release date:2004-03-09
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004

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