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2WZH
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BU of 2wzh by Molmil
BtGH84 D242N in complex with MeUMB-derived oxazoline
Descriptor: 2-METHYL-4,5-DIHYDRO-(1,2-DIDEOXY-ALPHA-D-GLUCOPYRANOSO)[2,1-D]-1,3-OXAZOLE, CALCIUM ION, GLYCEROL, ...
Authors:He, Y, Davies, G.J.
Deposit date:2009-11-30
Release date:2010-01-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase
J.Am.Chem.Soc., 132, 2010
3RCN
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BU of 3rcn by Molmil
Crystal Structure of Beta-N-Acetylhexosaminidase from Arthrobacter aurescens
Descriptor: ACETIC ACID, Beta-N-acetylhexosaminidase, GLYCEROL, ...
Authors:Kim, Y, Chhor, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2011-03-31
Release date:2011-06-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.514 Å)
Cite:Crystal Structure of Beta-N-Acetylhexosaminidase from Arthrobacter aurescens
To be Published
4PYS
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BU of 4pys by Molmil
The crystal structure of beta-N-acetylhexosaminidase from Bacteroides fragilis NCTC 9343
Descriptor: FORMIC ACID, GLYCEROL, ZINC ION, ...
Authors:Tan, K, Hatzos-Skintges, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2014-03-27
Release date:2014-06-18
Method:X-RAY DIFFRACTION (1.822 Å)
Cite:The crystal structure of beta-N-acetylhexosaminidase from Bacteroides fragilis NCTC 9343
To be Published
1QBB
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BU of 1qbb by Molmil
BACTERIAL CHITOBIASE COMPLEXED WITH CHITOBIOSE (DINAG)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHITOBIASE, SULFATE ION
Authors:Tews, I, Perrakis, A, Oppenheim, A, Dauter, Z, Wilson, K.S, Vorgias, C.E.
Deposit date:1996-06-07
Release date:1997-02-12
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease.
Nat.Struct.Biol., 3, 1996
1QBA
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BU of 1qba by Molmil
BACTERIAL CHITOBIASE, GLYCOSYL HYDROLASE FAMILY 20
Descriptor: CHITOBIASE, SULFATE ION
Authors:Tews, I, Perrakis, A, Oppenheim, A, Dauter, Z, Wilson, K.S, Vorgias, C.E.
Deposit date:1996-06-06
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Bacterial chitobiase structure provides insight into catalytic mechanism and the basis of Tay-Sachs disease.
Nat.Struct.Biol., 3, 1996
4JAW
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BU of 4jaw by Molmil
Crystal Structure of Lacto-N-Biosidase from Bifidobacterium bifidum complexed with LNB-thiazoline
Descriptor: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, Lacto-N-biosidase, SULFATE ION, ...
Authors:Ito, T, Katayama, T, Stubbs, K.A, Fushinobu, S.
Deposit date:2013-02-19
Release date:2013-03-20
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of a glycoside hydrolase family 20 lacto-N-biosidase from Bifidobacterium bifidum
J.Biol.Chem., 288, 2013
4H04
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BU of 4h04 by Molmil
Lacto-N-biosidase from Bifidobacterium bifidum
Descriptor: Lacto-N-biosidase, SULFATE ION, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ito, T, Katayama, T, Wada, J, Suzuki, R, Ashida, H, Wakagi, T, Yamamoto, K, Fushinobu, S.
Deposit date:2012-09-07
Release date:2013-03-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of a glycoside hydrolase family 20 lacto-N-biosidase from Bifidobacterium bifidum
J.Biol.Chem., 288, 2013
8BDP
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BU of 8bdp by Molmil
A GH20 family sulfoglycosidase Bt4394 in complex with NAG-thiazoline and sulfite
Descriptor: Beta-N-acetylhexosaminidase, CHLORIDE ION
Authors:Zhang, Z, He, Y, Jin, Y.
Deposit date:2022-10-19
Release date:2023-01-11
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases
Acs Catalysis, 2022
8BBL
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BU of 8bbl by Molmil
SGL a GH20 family sulfoglycosidase
Descriptor: Beta-N-acetylhexosaminidase
Authors:Dong, M.D, Roth, C.R, Jin, Y.J.
Deposit date:2022-10-13
Release date:2023-01-11
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.711 Å)
Cite:Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases
Acs Catalysis, 2022
7WDT
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BU of 7wdt by Molmil
6-sulfo-beta-D-N-acetylglucosaminidase from Bifidobacterium bifidum in complex with GlcNAc-6S
Descriptor: 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose, 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, ...
Authors:Yamada, C, Kashima, T, Fushinobu, S, Katoh, T, Katayama, T.
Deposit date:2021-12-22
Release date:2022-12-28
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem.
Nat.Chem.Biol., 19, 2023
7WDU
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BU of 7wdu by Molmil
6-sulfo-beta-D-N-acetylglucosaminidase from Bifidobacterium bifidum in complex with PUGNAc-6S
Descriptor: Beta-N-acetylhexosaminidase, CALCIUM ION, [[(3R,4R,5S,6R)-3-acetamido-4,5-bis(oxidanyl)-6-(sulfooxymethyl)oxan-2-ylidene]amino] N-phenylcarbamate
Authors:Kashima, T, Yamada, C, Fushinobu, S, Katoh, T, Katayama, T.
Deposit date:2021-12-22
Release date:2022-12-28
Last modified:2023-06-14
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:A bacterial sulfoglycosidase highlights mucin O-glycan breakdown in the gut ecosystem.
Nat.Chem.Biol., 19, 2023
1C7T
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BU of 1c7t by Molmil
BETA-N-ACETYLHEXOSAMINIDASE MUTANT E540D COMPLEXED WITH DI-N ACETYL-D-GLUCOSAMINE (CHITOBIASE)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-N-ACETYLHEXOSAMINIDASE, SULFATE ION
Authors:Prag, G, Papanikolau, Y, Tavlas, G, Vorgias, C.E, Petratos, K, Oppenheim, A.B.
Deposit date:2000-03-17
Release date:2000-09-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540.
J.Mol.Biol., 300, 2000
1C7S
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BU of 1c7s by Molmil
BETA-N-ACETYLHEXOSAMINIDASE MUTANT D539A COMPLEXED WITH DI-N-ACETYL-BETA-D-GLUCOSAMINE (CHITOBIASE)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BETA-N-ACETYLHEXOSAMINIDASE, SULFATE ION
Authors:Prag, G, Papanikolau, Y, Tavlas, G, Vorgias, C.E, Petratos, K, Oppenheim, A.B.
Deposit date:2000-03-14
Release date:2000-09-20
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540.
J.Mol.Biol., 300, 2000
1HP5
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BU of 1hp5 by Molmil
STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE COMPLEXED WITH INTERMEDIATE ANALOUGE NAG-THIAZOLINE
Descriptor: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, BETA-N-ACETYLHEXOSAMINIDASE, CHLORIDE ION, ...
Authors:Mark, B.L.
Deposit date:2000-12-12
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.
J.Biol.Chem., 276, 2001
5FD0
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BU of 5fd0 by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with NAGlucal
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-N-acetylhexosaminidase, GLYCEROL, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
5FCZ
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BU of 5fcz by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
Descriptor: 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, B-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
6YHH
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BU of 6yhh by Molmil
X-ray Structure of Flavobacterium johnsoniae chitobiase (FjGH20)
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-N-acetylglucosaminidase-like protein Glycoside hydrolase family 20, GLYCEROL
Authors:Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V.G.H, Pope, P.B, Branden, G, Larsbrink, J.
Deposit date:2020-03-30
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae.
Sci Rep, 10, 2020
6EZT
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BU of 6ezt by Molmil
Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase D437A inactive mutant from Vibrio harveyi
Descriptor: Beta-N-acetylglucosaminidase Nag2, DI(HYDROXYETHYL)ETHER, TETRAETHYLENE GLYCOL
Authors:Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W.
Deposit date:2017-11-16
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi
To Be Published
6EZR
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BU of 6ezr by Molmil
Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi
Descriptor: Beta-N-acetylglucosaminidase Nag2
Authors:Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W.
Deposit date:2017-11-16
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi
To Be Published
6EZS
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BU of 6ezs by Molmil
Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi in complex with N-acetylglucosamine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylglucosaminidase Nag2, MALONATE ION
Authors:Porfetye, A.T, Meekrathok, P, Burger, M, Vetter, I.R, Suginta, W.
Deposit date:2017-11-16
Release date:2018-12-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of GH20 Exo beta-N-Acetylglucosaminidase from Vibrio harveyi
To Be Published
1M04
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BU of 1m04 by Molmil
Mutant Streptomyces plicatus beta-hexosaminidase (D313N) in complex with product (GlcNAc)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Williams, S.J, Mark, B.L, Vocadlo, D.J, James, M.N.G, Withers, S.G.
Deposit date:2002-06-11
Release date:2002-12-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state.
J.Biol.Chem., 277, 2002
7EZT
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BU of 7ezt by Molmil
The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila
Descriptor: Beta-N-acetylhexosaminidase, MAGNESIUM ION
Authors:Bao, R, Li, C.C, Tang, X.Y, Zhu, Y.B, Song, Y.J, Zhao, N.L, Huang, Q, Mou, X.Y, Luo, G.H, Liu, T.G.
Deposit date:2021-06-02
Release date:2022-11-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Nucleotide binding as an allosteric regulatory mechanism for Akkermansia muciniphila beta- N -acetylhexosaminidase Am2136.
Gut Microbes, 14, 2022
1JAK
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BU of 1jak by Molmil
Streptomyces plicatus beta-N-acetylhexosaminidase in Complex with (2R,3R,4S,5R)-2-acetamido-3,4-dihydroxy-5-hydroxymethyl-piperidinium chloride (IFG)
Descriptor: (2R,3R,4S,5R)-2-ACETAMIDO-3,4-DIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, Beta-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Mark, B.L, Vocadlo, D.J, Zhao, D, Knapp, S, Withers, S.G, James, M.N.
Deposit date:2001-05-30
Release date:2001-11-21
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Biochemical and structural assessment of the 1-N-azasugar GalNAc-isofagomine as a potent family 20 beta-N-acetylhexosaminidase inhibitor.
J.Biol.Chem., 276, 2001
6YXZ
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BU of 6yxz by Molmil
Structure and activity of the GH20 beta-N-beta-N-acetylhexosaminidase from Bifidobacterium bifidum
Descriptor: Beta-N-acetylhexosaminidase, CHLORIDE ION, GLYCEROL, ...
Authors:He, Y, Jin, Y.
Deposit date:2020-05-04
Release date:2021-05-12
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure and activity of the GH20 beta-N-beta-N-acetylhexosaminidase from Bifidobacterium bifidum
To Be Published
6Z14
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BU of 6z14 by Molmil
Structure of Bifidobacterium bifidum GH20 beta-N-beta-N-acetylhexosaminidase E553Q variant in complex with 4MU-6SGlcNAc-derived oxazoline
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-N-acetylhexosaminidase, NITRATE ION, ...
Authors:He, Y, Jin, Y, Rizkallah, P, Chen, P.
Deposit date:2020-05-12
Release date:2021-05-19
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structure and activity of the GH20 beta-N-beta-N-acetylhexosaminidase from Bifidobacterium bifidum
To Be Published

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