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5EYV
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BU of 5eyv by Molmil
Crystal Structure of Adenylosuccinate lyase from Schistosoma mansoni in APO form.
Descriptor: Adenylosuccinate lyase
Authors:Romanello, L, Torini, J.R, Bird, L.E, Nettleship, J.E, Owens, R.J, Reddivari, Y, Brandao-Neto, J, Pereira, H.M.
Deposit date:2015-11-25
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
5E3V
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BU of 5e3v by Molmil
Truncated X-ray crystal structure of Adenylosuccinate Lyase from Salmonella typhimurium
Descriptor: Adenylosuccinate lyase
Authors:Banerjee, S, Agrawal, M.J, Murthy, M.R.N.
Deposit date:2015-10-04
Release date:2016-10-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystallographic and kinetic studies on Adenylosuccinate Lyase from Salmonella typhimurium
To Be Published
5D6B
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BU of 5d6b by Molmil
Human fumarase (wild type)
Descriptor: Fumarate hydratase, mitochondrial
Authors:Pereira de Padua, R.A, Nonato, M.C.
Deposit date:2015-08-11
Release date:2016-08-24
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase.
Acta Crystallogr F Struct Biol Commun, 70, 2014
5F91
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BU of 5f91 by Molmil
Fumarate hydratase of Mycobacterium tuberculosis in complex with formate and allosteric modulator (N-(5-(azepan-1-ylsulfonyl)-2-methoxyphenyl)-2-(4-oxo-3,4-dihydrophthalazin-1-yl)acetamide)
Descriptor: CHLORIDE ION, FORMIC ACID, Fumarate hydratase class II, ...
Authors:Kasbekar, M, Fischer, G, Mott, B.T, Yasgar, A, Hyvonen, M, Boshoff, H.I, Abell, C, Barry, C.E, Thomas, C.J.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Proc.Natl.Acad.Sci.USA, 113, 2016
5F92
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BU of 5f92 by Molmil
Fumarate hydratase of Mycobacterium tuberculosis in complex with formate
Descriptor: CHLORIDE ION, FORMIC ACID, Fumarate hydratase class II, ...
Authors:Kasbekar, M, Fischer, G, Mott, B.T, Yasgar, A, Hyvonen, M, Boshoff, H.I, Abell, C, Barry, C.E, Thomas, C.J.
Deposit date:2015-12-09
Release date:2016-06-22
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site.
Proc.Natl.Acad.Sci.USA, 113, 2016
5HW2
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Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with fumaric acid
Descriptor: 1,2-ETHANEDIOL, Adenylosuccinate lyase, FUMARIC ACID, ...
Authors:Chang, C, Maltseva, N, Kim, Y, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-01-28
Release date:2016-02-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.054 Å)
Cite:Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with fumaric acid
To Be Published
4NSL
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BU of 4nsl by Molmil
X-ray Crystal structure of Adenylosuccinate Lyase from Salmonella typhimurium
Descriptor: Adenylosuccinate lyase, PENTANE-1,5-DIAMINE
Authors:Banerjee, S, Agrawal, M.J, Murthy, M.R.N.
Deposit date:2013-11-28
Release date:2014-12-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic and kinetic studies on Adenylosuccinate Lyase from Salmonella typhimurium
To be Published
4MX2
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BU of 4mx2 by Molmil
Crystal Structure of adenylosuccinate lyase from Leishmania donovani
Descriptor: ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, GLYCEROL, ...
Authors:Wernimont, A.K, Loppnau, P, Dong, A, Krojer, T, Bradley, A, Bushell, S, von Delft, F, Robinson, D, Gilbert, I, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Mottaghi, K, Structural Genomics Consortium (SGC)
Deposit date:2013-09-25
Release date:2014-04-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of adenylosuccinate lyase from Leishmania donovani
To be Published
4NLE
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BU of 4nle by Molmil
Crystal structure of apo Adenylosuccinate Lyase from Mycobacterium smegmatis
Descriptor: Adenylosuccinate lyase
Authors:Banerjee, S, Murthy, M.R.N.
Deposit date:2013-11-14
Release date:2014-03-05
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme.
Febs J., 281, 2014
4EFC
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BU of 4efc by Molmil
Crystal Structure of Adenylosuccinate Lyase from Trypanosoma Brucei, Tb427tmp.160.5560
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, ...
Authors:Wernimont, A.K, Loppnau, P, Osman, K.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Robinson, D.A, Wyatt, P.G, Gilbert, I.H, Fairlamb, A.H, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC)
Deposit date:2012-03-29
Release date:2013-02-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of Adenylosuccinate Lyase from Trypanosoma Brucei, Tb427tmp.160.5560
To be Published
4HGV
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BU of 4hgv by Molmil
Crystal structure of a fumarate hydratase
Descriptor: Fumarate hydratase class II, SULFATE ION
Authors:Eswaramoorthy, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-10-08
Release date:2012-10-31
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystal structure of a fumarate hydratase
To be Published
4FFX
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Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Descriptor: Adenylosuccinate lyase
Authors:Deaton, M.K, Ray, S.P, Capodagli, G.C, Calkins, L.A.F, Sawle, L, Ghosh, K, Patterson, D, Pegan, S.D.
Deposit date:2012-06-01
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency-Associated Mutation.
Biochemistry, 51, 2012
4FLC
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BU of 4flc by Molmil
Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency Associated Mutation
Descriptor: Adenylosuccinate lyase
Authors:Deaton, M.K, Ray, S.P, Capodagli, G.C, Calkins, L.A.F, Sawle, L, Ghosh, K, Patterson, D, Pegan, S.D.
Deposit date:2012-06-14
Release date:2012-08-01
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Biochemical Characterization of Human Adenylosuccinate Lyase (ADSL) and the R303C ADSL Deficiency-Associated Mutation.
Biochemistry, 51, 2012
4ADM
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BU of 4adm by Molmil
Crystal structure of Rv1098c in complex with meso-tartrate
Descriptor: FUMARATE HYDRATASE CLASS II, GLYCEROL, S,R MESO-TARTARIC ACID
Authors:Mechaly, A.E, Haouz, A, Miras, I, Weber, P, Shepard, W, Cole, S, Alzari, P.M, Bellinzoni, M.
Deposit date:2011-12-27
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4APB
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BU of 4apb by Molmil
Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318C in complex with fumarate
Descriptor: CALCIUM ION, FUMARATE HYDRATASE CLASS II, FUMARIC ACID
Authors:Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
Deposit date:2012-03-31
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4ADL
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BU of 4adl by Molmil
Crystal structures of Rv1098c in complex with malate
Descriptor: (2S)-2-hydroxybutanedioic acid, FUMARATE HYDRATASE CLASS II
Authors:Mechaly, A.E, Haouz, A, Miras, I, Weber, P, Shepard, W, Cole, S, Alzari, P.M, Bellinzoni, M.
Deposit date:2011-12-26
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4APA
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BU of 4apa by Molmil
Crystal structure of Mycobacterium tuberculosis fumarase (Rv1098c) S318A in apo form
Descriptor: FUMARATE HYDRATASE CLASS II
Authors:Bellinzoni, M, Haouz, A, Mechaly, A.E, Alzari, P.M.
Deposit date:2012-03-31
Release date:2012-04-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Conformational Changes Upon Ligand Binding in the Essential Class II Fumarase Rv1098C from Mycobacterium Tuberculosis.
FEBS Lett., 586, 2012
4EEI
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BU of 4eei by Molmil
Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
Descriptor: 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase, ...
Authors:Maltseva, N, Kim, Y, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-03-28
Release date:2012-04-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.921 Å)
Cite:Crystal Structure of Adenylosuccinate Lyase from Francisella tularensis Complexed with AMP and Succinate
To be Published
3TV2
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BU of 3tv2 by Molmil
Structure of a class II fumarate hydratase from Burkholderia pseudomallei
Descriptor: Fumarate hydratase, class II, SODIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-09-19
Release date:2011-09-28
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of a class II fumarate hydratase from Burkholderia pseudomallei
To be Published
3R6Q
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BU of 3r6q by Molmil
A triclinic-lattice structure of aspartase from Bacillus sp. YM55-1
Descriptor: Aspartase, CALCIUM ION
Authors:Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H.
Deposit date:2011-03-22
Release date:2011-07-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for the catalytic mechanism of aspartate ammonia lyase.
Biochemistry, 50, 2011
3R6Y
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BU of 3r6y by Molmil
Crystal structure of chymotrypsin-treated aspartase from Bacillus sp. YM55-1
Descriptor: Aspartase, CALCIUM ION
Authors:Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H.
Deposit date:2011-03-22
Release date:2011-07-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for the catalytic mechanism of aspartate ammonia lyase.
Biochemistry, 50, 2011
3R6V
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BU of 3r6v by Molmil
Crystal structure of aspartase from Bacillus sp. YM55-1 with bound L-aspartate
Descriptor: ASPARTIC ACID, Aspartase, CALCIUM ION
Authors:Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H.
Deposit date:2011-03-22
Release date:2011-07-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the catalytic mechanism of aspartate ammonia lyase.
Biochemistry, 50, 2011
3RD8
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BU of 3rd8 by Molmil
Crystal structure of fumarate hydratase class II Mycobacterium smegmatis
Descriptor: Fumarate hydratase class II
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-04-01
Release date:2011-06-08
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3RRP
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BU of 3rrp by Molmil
Crystal structure of fumarate hydratase Fum from Mycobacterium abscessus with malate bound
Descriptor: (2S)-2-hydroxybutanedioic acid, 1,2-ETHANEDIOL, Probable fumarate hydratase Fum
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-04-29
Release date:2011-05-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3QBP
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BU of 3qbp by Molmil
Crystal structure of fumarase Fum from Mycobacterium marinum
Descriptor: Fumarase Fum
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2011-01-13
Release date:2011-01-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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