4NLE

Crystal structure of apo Adenylosuccinate Lyase from Mycobacterium smegmatis

Summary for 4NLE

Entry DOI	10.2210/pdb4nle/pdb
Descriptor	Adenylosuccinate lyase (2 entities in total)
Functional Keywords	purine biosynthesis, purine salvage pathway, homotetramer, catalysis, aspartase/fumarase superfamily, lyase
Biological source	Mycobacterium smegmatis
Total number of polymer chains	2
Total formula weight	106549.22
Authors	Banerjee, S.,Murthy, M.R.N. (deposition date: 2013-11-14, release date: 2014-03-05, Last modification date: 2023-11-08)
Primary citation	Banerjee, S.,Agrawal, M.J.,Mishra, D.,Sharan, S.,Balaram, H.,Savithri, H.S.,Murthy, M.R. Structural and kinetic studies on adenylosuccinate lyase from Mycobacterium smegmatis and Mycobacterium tuberculosis provide new insights on the catalytic residues of the enzyme. Febs J., 281:1642-1658, 2014 Cited by PubMed: 24479855 DOI: 10.1111/febs.12730 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.16 Å)

Structure validation